| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 34 | 34 | 5 | 13 | 3.37 | .285 | 1.17 | 7.7 | 2.9 | 10.4 | 208.1 | 177 | 80 | 78 | 27 | 67 | 241 | 0 | 0 | 0 | 0 | 22 | 5 | 8 | 3.41 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 82 | 33 | 33 | 4 | 10 | 4.98 | .313 | 1.35 | 9.1 | 3.0 | 7.1 | 159.0 | 161 | 88 | 88 | 22 | 53 | 125 | 0 | 0 | 0 | 0 | 6 | 3 | 5 | 4.28 |
| SP | Kirby, G.Kirby, George # >> | 27 | 2025 | R | 66 | 32 | 32 | 8 | 16 | 5.82 | .341 | 1.49 | 10.3 | 3.2 | 9.5 | 174.2 | 199 | 117 | 113 | 27 | 61 | 183 | 0 | 0 | 0 | 0 | 9 | 11 | 2 | 4.16 |
| SP | Burrows, M.Burrows, Mike >> | 25 | 2025 | R | 65 | 31 | 31 | 4 | 10 | 5.68 | .357 | 1.63 | 10.7 | 4.0 | 8.7 | 130.0 | 154 | 86 | 82 | 25 | 58 | 125 | 0 | 0 | 0 | 0 | 2 | 5 | 4 | 5.03 |
| SP | Kremer, D.Kremer, Dean >> | 29 | 2025 | R | 57 | 31 | 31 | 11 | 9 | 4.44 | .350 | 1.58 | 10.3 | 3.9 | 6.6 | 176.1 | 201 | 93 | 87 | 21 | 77 | 130 | 0 | 0 | 0 | 0 | 11 | 7 | 10 | 4.51 |
| RP | Raley, B.Raley, Brooks >> | 37 | 2025 | L | 97 | 83 | 0 | 5 | 4 | 2.74 | .250 | 0.94 | 6.0 | 2.5 | 9.5 | 128.1 | 85 | 43 | 39 | 5 | 36 | 135 | 0 | 2 | 6 | 0 | 0 | 7 | 0 | 2.41 |
| RP | Strahm, M.Strahm, Matt # >> | 33 | 2025 | L | 73 | 89 | 0 | 9 | 6 | 3.88 | .270 | 1.06 | 7.3 | 2.3 | 10.7 | 118.1 | 96 | 53 | 51 | 13 | 30 | 140 | 0 | 9 | 5 | 0 | 0 | 5 | 7 | 2.95 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 62 | 78 | 0 | 9 | 7 | 4.57 | .317 | 1.35 | 8.8 | 3.3 | 6.9 | 100.1 | 98 | 55 | 51 | 19 | 37 | 77 | 0 | 10 | 6 | 0 | 0 | 5 | 4 | 5.19 |
| RP | Ferguson, C.Ferguson, Caleb >> | 28 | 2025 | L | 54 | 60 | 0 | 3 | 5 | 3.04 | .326 | 1.44 | 8.5 | 4.4 | 7.4 | 71.0 | 67 | 25 | 24 | 9 | 35 | 58 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 4.54 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 50 | 2 | 1 | 0 | 0 | 11.05 | .450 | 2.45 | 15.4 | 7.7 | 7.7 | 7.1 | 12 | 9 | 9 | 0 | 6 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.86 |
| SP | Priester, Q.Priester, Quinn >> | 24 | 2025 | R | 54 | 49 | 0 | 3 | 8 | 4.62 | .372 | 1.76 | 11.1 | 4.8 | 7.1 | 60.1 | 74 | 34 | 31 | 5 | 32 | 47 | 0 | 10 | 1 | 0 | 0 | 1 | 2 | 4.17 |