| SP | Skubal, T.Skubal, Tarik # $ >> | 28 | 2025 | L | 100 | 7 | 7 | 1 | 3 | 4.97 | .313 | 1.27 | 9.7 | 2.0 | 10.8 | 41.2 | 44 | 23 | 23 | 7 | 9 | 49 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 3.78 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 88 | 7 | 7 | 3 | 2 | 5.18 | .361 | 1.64 | 10.1 | 4.6 | 9.0 | 33.0 | 37 | 19 | 19 | 5 | 17 | 33 | 0 | 0 | 0 | 0 | 1 | 2 | 2 | 4.70 |
| SP | Imanaga, S.Imanaga, Shota $ >> | 31 | 2025 | L | 83 | 7 | 7 | 4 | 2 | 3.76 | .320 | 1.33 | 8.8 | 3.3 | 6.2 | 38.1 | 37 | 17 | 16 | 5 | 14 | 26 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.68 |
| SP | Abbott, A.Abbott, Andrew >> | 26 | 2025 | L | 71 | 7 | 7 | 0 | 2 | 3.98 | .345 | 1.52 | 9.6 | 4.4 | 8.4 | 31.2 | 33 | 17 | 14 | 6 | 15 | 29 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 5.29 |
| SP | Woods Richardson, S.Woods Richardson, Simeon >> | 24 | 2025 | R | 60 | 7 | 6 | 0 | 1 | 6.00 | .400 | 2.00 | 11.6 | 6.4 | 5.1 | 21.0 | 27 | 14 | 14 | 5 | 15 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.10 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 22 | 0 | 1 | 0 | 1.98 | .255 | 1.02 | 4.7 | 4.7 | 10.3 | 27.1 | 14 | 7 | 6 | 1 | 14 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.74 |
| RP | Jansen, K.Jansen, Kenley $ >> | 37 | 2025 | R | 89 | 22 | 0 | 3 | 1 | 2.81 | .260 | 1.05 | 5.8 | 4.0 | 8.6 | 25.2 | 16 | 12 | 8 | 0 | 11 | 24 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.40 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 82 | 18 | 0 | 0 | 0 | 1.93 | .278 | 1.16 | 5.1 | 5.5 | 10.6 | 23.1 | 13 | 5 | 5 | 1 | 14 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.04 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 77 | 14 | 0 | 3 | 1 | 7.30 | .413 | 2.11 | 10.5 | 9.0 | 7.5 | 12.1 | 14 | 10 | 10 | 2 | 12 | 10 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 6.50 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 77 | 11 | 0 | 0 | 2 | 2.70 | .333 | 1.50 | 9.0 | 4.8 | 9.0 | 13.1 | 13 | 4 | 4 | 0 | 7 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.62 |
| RP | Estevez, C.Estevez, Carlos >> | 32 | 2025 | R | 70 | 14 | 0 | 4 | 1 | 6.20 | .322 | 1.43 | 10.4 | 2.7 | 7.2 | 20.1 | 23 | 15 | 14 | 6 | 6 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.20 |