| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 83 | 33 | 33 | 14 | 12 | 3.94 | .294 | 1.22 | 9.0 | 2.0 | 5.0 | 253.1 | 252 | 119 | 111 | 20 | 57 | 141 | 9 | 0 | 0 | 2 | 19 | 7 | 3 | 3.67 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 32 | 32 | 13 | 13 | 4.56 | .309 | 1.29 | 9.5 | 2.1 | 5.4 | 235.0 | 249 | 121 | 119 | 23 | 54 | 142 | 7 | 0 | 0 | 1 | 14 | 12 | 3 | 3.91 |
| SP | Reulbach, E.Reulbach, Ed # >> | 24 | 1906 | R | 60 | 31 | 31 | 9 | 14 | 4.74 | .333 | 1.46 | 8.2 | 4.9 | 5.0 | 203.0 | 185 | 114 | 107 | 14 | 111 | 112 | 5 | 0 | 0 | 0 | 15 | 8 | 4 | 4.55 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 80 | 0 | 9 | 6 | 3.86 | .302 | 1.29 | 9.0 | 2.6 | 7.5 | 102.2 | 102 | 47 | 44 | 9 | 30 | 85 | 0 | 9 | 2 | 0 | 0 | 1 | 3 | 3.39 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 77 | 0 | 0 | 4 | 3.92 | .262 | 1.06 | 6.9 | 2.7 | 8.2 | 87.1 | 67 | 39 | 38 | 7 | 26 | 79 | 0 | 10 | 3 | 0 | 0 | 0 | 4 | 3.13 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 37 | 0 | 2 | 1 | 3.27 | .313 | 1.34 | 7.0 | 5.1 | 8.0 | 44.0 | 34 | 16 | 16 | 2 | 25 | 39 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.59 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 55 | 4 | 0 | 1 | 0 | 0.00 | .167 | 0.60 | 6.0 | 0.0 | 6.0 | 3.1 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.67 |