| SP | Koufax, S.Koufax, Sandy † # >> | 30 | 1965 | L | 97 | 35 | 35 | 18 | 10 | 3.16 | .270 | 1.10 | 7.1 | 2.9 | 7.9 | 273.1 | 214 | 100 | 96 | 27 | 87 | 239 | 12 | 0 | 0 | 4 | 23 | 2 | 7 | 3.51 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 34 | 34 | 18 | 12 | 4.60 | .319 | 1.38 | 9.7 | 2.7 | 6.8 | 235.0 | 254 | 122 | 120 | 21 | 71 | 177 | 9 | 0 | 0 | 2 | 13 | 6 | 8 | 3.64 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 33 | 33 | 17 | 11 | 4.18 | .291 | 1.19 | 9.1 | 1.7 | 5.0 | 223.2 | 226 | 114 | 104 | 29 | 41 | 125 | 9 | 0 | 0 | 3 | 18 | 8 | 2 | 4.23 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 78 | 0 | 4 | 8 | 3.54 | .271 | 1.09 | 6.0 | 3.8 | 7.7 | 112.0 | 75 | 44 | 44 | 15 | 47 | 96 | 0 | 13 | 1 | 0 | 0 | 3 | 0 | 4.37 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 53 | 0 | 8 | 4 | 2.68 | .263 | 1.04 | 6.9 | 2.4 | 9.0 | 57.0 | 44 | 17 | 17 | 6 | 15 | 57 | 0 | 8 | 4 | 0 | 0 | 2 | 1 | 3.26 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 14 | 0 | 0 | 0 | 7.15 | .358 | 1.68 | 8.2 | 7.4 | 6.5 | 11.1 | 10 | 9 | 9 | 2 | 9 | 8 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 6.36 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 20 | 0 | 0 | 1 | 5.73 | .320 | 1.36 | 7.0 | 5.3 | 6.1 | 22.0 | 17 | 14 | 14 | 3 | 13 | 15 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 5.32 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 20 | 0 | 3 | 4 | 3.66 | .275 | 1.13 | 7.8 | 2.3 | 3.4 | 93.1 | 81 | 43 | 38 | 15 | 24 | 35 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.15 |