| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 92 | 33 | 33 | 16 | 8 | 3.39 | .291 | 1.22 | 7.9 | 3.1 | 9.5 | 212.2 | 187 | 89 | 80 | 16 | 72 | 223 | 4 | 0 | 0 | 4 | 20 | 3 | 10 | 2.94 |
| SP | Sheets, B.Sheets, Ben † >> | 26 | 2004 | R | 90 | 33 | 33 | 17 | 7 | 3.20 | .278 | 1.13 | 8.2 | 2.0 | 9.8 | 211.0 | 192 | 85 | 75 | 34 | 47 | 230 | 4 | 0 | 0 | 2 | 23 | 5 | 1 | 3.65 |
| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 88 | 32 | 32 | 8 | 10 | 4.89 | .322 | 1.38 | 9.3 | 3.2 | 9.4 | 151.0 | 156 | 88 | 82 | 17 | 53 | 157 | 0 | 0 | 0 | 0 | 9 | 6 | 3 | 3.56 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 69 | 28 | 20 | 9 | 8 | 4.48 | .309 | 1.30 | 8.5 | 3.2 | 6.1 | 132.2 | 125 | 70 | 66 | 17 | 47 | 90 | 0 | 0 | 0 | 0 | 6 | 6 | 2 | 4.52 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 32 | 29 | 11 | 11 | 4.78 | .336 | 1.49 | 10.6 | 2.8 | 7.3 | 152.2 | 179 | 90 | 81 | 25 | 48 | 124 | 0 | 0 | 0 | 0 | 12 | 5 | 3 | 4.55 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 67 | 0 | 4 | 3 | 3.78 | .284 | 1.13 | 7.9 | 2.3 | 6.2 | 83.1 | 73 | 36 | 35 | 11 | 21 | 57 | 0 | 0 | 3 | 0 | 0 | 5 | 3 | 4.29 |
| CL | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 87 | 68 | 0 | 2 | 3 | 2.22 | .268 | 1.04 | 6.8 | 2.6 | 5.5 | 73.0 | 55 | 22 | 18 | 5 | 21 | 45 | 0 | 34 | 0 | 0 | 0 | 4 | 1 | 3.68 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 29 | 0 | 1 | 1 | 4.11 | .313 | 1.34 | 7.2 | 5.1 | 10.2 | 30.2 | 24 | 14 | 14 | 3 | 17 | 34 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.83 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 75 | 65 | 0 | 7 | 3 | 4.30 | .295 | 1.23 | 8.1 | 3.0 | 9.6 | 73.1 | 66 | 35 | 35 | 15 | 24 | 78 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 4.60 |
| RP | Gordon, T.Gordon, Tom # >> | 37 | 2004 | R | 81 | 54 | 0 | 3 | 1 | 6.79 | .348 | 1.56 | 9.0 | 5.2 | 9.3 | 55.2 | 55 | 43 | 42 | 10 | 32 | 57 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.15 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 77 | 38 | 11 | 9 | 6 | 6.47 | .352 | 1.60 | 10.6 | 3.7 | 7.0 | 121.0 | 143 | 88 | 87 | 30 | 50 | 94 | 0 | 0 | 1 | 0 | 2 | 4 | 2 | 6.01 |