| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 18 | 18 | 2 | 9 | 6.64 | .352 | 1.60 | 11.3 | 3.1 | 6.7 | 99.0 | 124 | 77 | 73 | 24 | 34 | 74 | 1 | 0 | 0 | 0 | 7 | 3 | 0 | 5.78 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 84 | 19 | 18 | 8 | 7 | 5.09 | .301 | 1.28 | 8.5 | 3.1 | 7.2 | 106.0 | 100 | 62 | 60 | 18 | 36 | 85 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 4.65 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 20 | 18 | 3 | 8 | 6.80 | .377 | 1.76 | 11.3 | 4.6 | 8.6 | 92.2 | 116 | 75 | 70 | 17 | 47 | 88 | 0 | 0 | 0 | 0 | 4 | 5 | 0 | 5.18 |
| SU | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 90 | 50 | 0 | 1 | 3 | 5.00 | .296 | 1.24 | 7.3 | 3.8 | 10.2 | 54.0 | 44 | 32 | 30 | 9 | 23 | 61 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 4.24 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 53 | 48 | 0 | 1 | 1 | 4.88 | .331 | 1.46 | 8.8 | 4.4 | 8.3 | 55.1 | 54 | 31 | 30 | 12 | 27 | 51 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 5.51 |