| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 99 | 20 | 20 | 7 | 10 | 4.05 | .283 | 1.15 | 8.1 | 2.4 | 9.3 | 126.2 | 113 | 58 | 57 | 19 | 33 | 130 | 2 | 0 | 0 | 1 | 11 | 4 | 1 | 3.78 |
| SP | Lowe, D.Lowe, Derek † # >> | 29 | 2002 | R | 89 | 18 | 18 | 12 | 3 | 3.06 | .258 | 1.03 | 6.6 | 2.6 | 6.3 | 126.1 | 93 | 46 | 43 | 15 | 37 | 88 | 4 | 0 | 0 | 1 | 12 | 2 | 1 | 4.08 |
| SP | Pettitte, A.Pettitte, Andy † >> | 33 | 2005 | L | 77 | 18 | 18 | 8 | 2 | 4.43 | .288 | 1.20 | 8.1 | 2.8 | 5.9 | 105.2 | 94 | 52 | 52 | 20 | 33 | 69 | 1 | 0 | 0 | 1 | 10 | 1 | 5 | 5.13 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 98 | 34 | 0 | 6 | 2 | 1.40 | .227 | 0.85 | 5.0 | 2.8 | 9.2 | 38.2 | 21 | 6 | 6 | 2 | 12 | 39 | 0 | 20 | 3 | 0 | 0 | 1 | 2 | 2.66 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 37 | 0 | 4 | 2 | 2.55 | .302 | 1.28 | 7.5 | 4.1 | 8.8 | 42.1 | 35 | 15 | 12 | 7 | 19 | 41 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.64 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 67 | 31 | 0 | 2 | 0 | 1.67 | .198 | 0.71 | 4.2 | 2.3 | 10.4 | 32.1 | 15 | 7 | 6 | 5 | 8 | 37 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.56 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 51 | 46 | 0 | 2 | 1 | 3.47 | .283 | 1.18 | 7.8 | 3.0 | 12.3 | 36.1 | 31 | 14 | 14 | 4 | 12 | 49 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 58 | 18 | 0 | 0 | 1 | 4.20 | .318 | 1.40 | 5.4 | 7.2 | 9.0 | 15.0 | 9 | 7 | 7 | 3 | 12 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 77 | 20 | 0 | 0 | 0 | 3.97 | .327 | 1.46 | 9.4 | 4.1 | 9.4 | 22.2 | 23 | 10 | 10 | 4 | 10 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.64 |