| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 92 | 19 | 19 | 10 | 5 | 2.57 | .253 | 1.00 | 7.3 | 1.7 | 7.9 | 150.2 | 121 | 46 | 43 | 12 | 29 | 132 | 3 | 0 | 0 | 0 | 14 | 3 | 2 | 2.92 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 97 | 18 | 18 | 0 | 4 | 3.27 | .302 | 1.25 | 7.8 | 3.5 | 7.0 | 44.0 | 38 | 16 | 16 | 3 | 17 | 34 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 3.64 |
| SP | Greinke, Z.Greinke, Zack >> | 36 | 2019 | R | 72 | 18 | 18 | 8 | 7 | 3.98 | .280 | 1.13 | 8.0 | 2.2 | 6.2 | 120.0 | 107 | 53 | 53 | 13 | 29 | 83 | 2 | 0 | 0 | 0 | 11 | 4 | 0 | 3.85 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 60 | 19 | 18 | 9 | 4 | 4.21 | .308 | 1.31 | 8.2 | 3.7 | 5.2 | 113.1 | 103 | 59 | 53 | 20 | 46 | 65 | 0 | 0 | 0 | 0 | 12 | 2 | 0 | 5.42 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 71 | 50 | 0 | 5 | 2 | 4.85 | .328 | 1.45 | 7.5 | 5.6 | 9.3 | 59.1 | 49 | 32 | 32 | 10 | 37 | 61 | 0 | 2 | 2 | 0 | 0 | 1 | 4 | 5.07 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 70 | 39 | 0 | 1 | 2 | 1.91 | .291 | 1.19 | 6.3 | 4.4 | 6.5 | 47.0 | 33 | 13 | 10 | 3 | 23 | 34 | 0 | 7 | 2 | 0 | 0 | 2 | 2 | 3.98 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 59 | 25 | 0 | 3 | 2 | 2.70 | .322 | 1.43 | 7.3 | 5.9 | 6.9 | 26.2 | 21 | 8 | 8 | 1 | 17 | 20 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.92 |
| RP | Hernandez, D.Hernandez, David >> | 27 | 2012 | R | 47 | 19 | 0 | 2 | 1 | 3.57 | .303 | 1.30 | 6.9 | 5.3 | 10.1 | 17.2 | 13 | 7 | 7 | 2 | 10 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.06 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 60 | 19 | 0 | 0 | 0 | 3.80 | .312 | 1.27 | 6.0 | 5.6 | 10.7 | 21.1 | 14 | 9 | 9 | 1 | 13 | 25 | 0 | 2 | 1 | 0 | 0 | 2 | 2 | 3.38 |
| SP | Gilbert, T.Gilbert, Tyler >> | 27 | 2021 | L | 66 | 24 | 0 | 6 | 2 | 3.19 | .287 | 1.21 | 8.0 | 2.9 | 5.4 | 62.0 | 55 | 25 | 22 | 7 | 20 | 37 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.24 |