| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 81 | 20 | 20 | 11 | 5 | 3.78 | .267 | 1.07 | 7.5 | 2.2 | 9.5 | 138.0 | 115 | 58 | 58 | 17 | 33 | 145 | 3 | 0 | 0 | 2 | 11 | 3 | 4 | 3.28 |
| SP | Greinke, Z.Greinke, Zack # >> | 36 | 2019 | R | 65 | 19 | 19 | 8 | 5 | 4.11 | .296 | 1.24 | 8.9 | 2.4 | 5.6 | 124.2 | 122 | 62 | 57 | 19 | 33 | 77 | 1 | 0 | 0 | 1 | 11 | 2 | 2 | 4.60 |
| SP | Kelly, M.Kelly, Merrill >> | 31 | 2020 | R | 46 | 19 | 19 | 0 | 5 | 5.63 | .338 | 1.38 | 10.2 | 2.3 | 6.5 | 46.1 | 52 | 32 | 29 | 9 | 12 | 33 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 5.35 |
| RP | Ramirez, N.Ramirez, Noe † >> | 31 | 2021 | R | 66 | 54 | 0 | 6 | 0 | 3.33 | .306 | 1.31 | 7.8 | 4.0 | 5.3 | 70.1 | 61 | 27 | 26 | 9 | 31 | 41 | 0 | 6 | 1 | 0 | 0 | 1 | 2 | 4.87 |
| RP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 65 | 49 | 0 | 5 | 3 | 2.57 | .252 | 0.99 | 6.3 | 2.6 | 6.1 | 84.0 | 59 | 26 | 24 | 9 | 24 | 57 | 0 | 8 | 3 | 0 | 0 | 2 | 2 | 3.96 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 36 | 0 | 5 | 2 | 2.98 | .273 | 1.10 | 4.8 | 5.2 | 11.6 | 45.1 | 24 | 16 | 15 | 5 | 26 | 58 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 3.67 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 46 | 18 | 0 | 3 | 0 | 2.91 | .244 | 0.92 | 5.1 | 3.4 | 7.7 | 21.2 | 12 | 7 | 7 | 2 | 8 | 18 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.81 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 45 | 10 | 0 | 1 | 0 | 1.38 | .278 | 1.15 | 6.2 | 4.2 | 15.2 | 13.0 | 9 | 2 | 2 | 1 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Slaten, J.Slaten, Justin >> | 26 | 2024 | R | 31 | 3 | 0 | 0 | 0 | 7.36 | .389 | 1.91 | 21.0 | 0.0 | 9.0 | 3.2 | 7 | 3 | 3 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| RP | McGough, S.McGough, Scott >> | 33 | 2023 | R | 21 | 18 | 0 | 1 | 0 | 7.02 | .367 | 1.74 | 10.1 | 6.2 | 12.4 | 16.2 | 18 | 13 | 13 | 2 | 11 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.94 |
| SP | Roberts, R.Roberts, Robin >> | 39 | 1965 | R | 34 | 10 | 0 | 3 | 1 | 3.57 | .244 | 0.95 | 6.4 | 2.2 | 7.0 | 45.1 | 32 | 19 | 18 | 6 | 11 | 35 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.98 |