| SP | deGrom, J.deGrom, Jacob >> | 30 | 2018 | R | 91 | 18 | 18 | 5 | 7 | 3.45 | .284 | 1.17 | 8.6 | 2.0 | 8.9 | 120.0 | 114 | 49 | 46 | 11 | 26 | 118 | 3 | 0 | 0 | 0 | 12 | 3 | 1 | 2.95 |
| SP | Scherzer, M.Scherzer, Max † >> | 38 | 2022 | R | 89 | 18 | 18 | 10 | 3 | 2.23 | .243 | 0.94 | 6.8 | 1.7 | 8.7 | 125.1 | 94 | 31 | 31 | 10 | 24 | 121 | 2 | 0 | 0 | 2 | 14 | 3 | 3 | 2.75 |
| SP | Harvey, M.Harvey, Matt # >> | 24 | 2013 | R | 82 | 19 | 19 | 9 | 7 | 3.23 | .263 | 1.04 | 7.5 | 1.9 | 8.7 | 136.2 | 114 | 51 | 49 | 18 | 28 | 131 | 5 | 0 | 0 | 1 | 11 | 4 | 0 | 3.50 |
| SP | Martinez, P.Martinez, Pedro >> | 34 | 2005 | R | 75 | 18 | 18 | 10 | 5 | 3.24 | .243 | 0.94 | 6.7 | 1.8 | 6.1 | 127.2 | 94 | 46 | 46 | 17 | 26 | 86 | 7 | 0 | 0 | 4 | 11 | 3 | 2 | 4.07 |
| SP | Fernandez, S.Fernandez, Sid † >> | 26 | 1988 | L | 68 | 18 | 18 | 12 | 3 | 3.16 | .278 | 1.15 | 6.8 | 3.6 | 8.4 | 116.2 | 87 | 41 | 41 | 12 | 47 | 108 | 0 | 0 | 0 | 0 | 13 | 1 | 2 | 3.72 |
| RP | Verrett, L.Verrett, Logan >> | 25 | 2015 | R | 72 | 36 | 0 | 2 | 3 | 2.52 | .254 | 1.02 | 6.6 | 2.7 | 5.3 | 60.2 | 44 | 17 | 17 | 5 | 18 | 35 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.82 |
| RP | Wagner, B.Wagner, Billy >> | 37 | 2008 | L | 69 | 46 | 0 | 1 | 0 | 1.82 | .258 | 1.01 | 7.8 | 1.6 | 7.4 | 29.2 | 25 | 6 | 6 | 1 | 5 | 24 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.41 |
| RP | Nunez, D.Nunez, Dedniel >> | 28 | 2024 | R | 66 | 26 | 0 | 0 | 1 | 1.75 | .245 | 0.97 | 5.5 | 3.3 | 11.0 | 36.0 | 22 | 7 | 7 | 3 | 13 | 44 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.72 |
| RP | Lockwood, S.Lockwood, Skip >> | 30 | 1976 | R | 54 | 17 | 0 | 2 | 2 | 4.05 | .302 | 1.30 | 7.7 | 4.1 | 8.1 | 20.0 | 17 | 9 | 9 | 2 | 9 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.85 |
| RP | Robles, H.Robles, Hansel >> | 24 | 2015 | R | 49 | 9 | 0 | 0 | 2 | 2.70 | .268 | 1.10 | 6.3 | 3.6 | 6.3 | 10.0 | 7 | 3 | 3 | 1 | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.10 |
| RP | McLean, N.McLean, Nolan >> | 23 | 2025 | R | 43 | 11 | 0 | 0 | 0 | 2.14 | .250 | 1.00 | 4.3 | 4.7 | 12.0 | 21.0 | 10 | 5 | 5 | 2 | 11 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.14 |