| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 28 | 28 | 13 | 9 | 3.55 | .288 | 1.19 | 7.4 | 3.3 | 4.9 | 215.1 | 176 | 90 | 85 | 31 | 80 | 118 | 14 | 0 | 0 | 3 | 16 | 5 | 1 | 4.96 |
| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 80 | 28 | 28 | 11 | 11 | 3.30 | .284 | 1.19 | 6.2 | 4.6 | 7.4 | 171.2 | 117 | 66 | 63 | 13 | 87 | 140 | 0 | 0 | 0 | 0 | 18 | 0 | 7 | 3.88 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 27 | 27 | 9 | 11 | 5.99 | .344 | 1.54 | 10.4 | 3.5 | 5.1 | 160.2 | 184 | 110 | 107 | 23 | 63 | 91 | 7 | 0 | 0 | 0 | 8 | 6 | 1 | 5.03 |
| SP | Hughes, T.Hughes, Tom # >> | 31 | 1915 | R | 63 | 26 | 26 | 8 | 12 | 5.14 | .306 | 1.31 | 9.5 | 2.3 | 4.6 | 150.2 | 158 | 88 | 86 | 21 | 39 | 76 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 4.63 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 70 | 0 | 5 | 5 | 3.52 | .290 | 1.21 | 7.1 | 3.7 | 9.2 | 92.0 | 73 | 37 | 36 | 11 | 38 | 94 | 0 | 4 | 3 | 0 | 0 | 2 | 1 | 3.82 |
| RP | Clippard, T.Clippard, Tyler # >> | 26 | 2011 | R | 80 | 61 | 0 | 2 | 5 | 6.00 | .347 | 1.54 | 8.5 | 5.3 | 8.3 | 69.0 | 65 | 49 | 46 | 18 | 41 | 64 | 0 | 8 | 0 | 0 | 0 | 4 | 1 | 6.49 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 29 | 0 | 2 | 3 | 3.35 | .298 | 1.25 | 7.3 | 4.1 | 9.2 | 37.2 | 30 | 15 | 14 | 5 | 17 | 38 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.16 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 1 | 0 | 0 | 4.70 | .361 | 1.57 | 11.6 | 3.9 | 7.7 | 7.2 | 9 | 4 | 4 | 1 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.86 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 16 | 0 | 1 | 3 | 6.94 | .340 | 1.54 | 11.3 | 2.7 | 3.5 | 23.1 | 29 | 18 | 18 | 4 | 7 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.39 |