| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 28 | 28 | 9 | 12 | 4.82 | .318 | 1.39 | 10.0 | 2.6 | 5.2 | 170.0 | 188 | 99 | 91 | 21 | 49 | 98 | 0 | 0 | 0 | 0 | 13 | 1 | 4 | 4.34 |
| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 29 | 29 | 10 | 11 | 4.69 | .299 | 1.27 | 8.7 | 2.8 | 8.3 | 170.2 | 165 | 92 | 89 | 27 | 52 | 156 | 1 | 0 | 0 | 1 | 13 | 1 | 2 | 4.16 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 27 | 27 | 9 | 13 | 4.75 | .298 | 1.24 | 8.3 | 2.9 | 8.2 | 138.1 | 127 | 76 | 73 | 16 | 45 | 126 | 0 | 0 | 0 | 0 | 10 | 4 | 2 | 3.75 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 66 | 0 | 3 | 6 | 3.53 | .310 | 1.32 | 8.2 | 3.7 | 8.3 | 97.0 | 88 | 41 | 38 | 10 | 40 | 89 | 0 | 1 | 3 | 0 | 0 | 3 | 1 | 3.84 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 61 | 0 | 3 | 2 | 2.79 | .283 | 1.14 | 7.0 | 3.3 | 10.9 | 71.0 | 55 | 24 | 22 | 6 | 26 | 86 | 0 | 1 | 1 | 0 | 0 | 3 | 2 | 2.90 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 52 | 0 | 1 | 1 | 3.96 | .319 | 1.40 | 8.3 | 4.4 | 7.8 | 61.1 | 56 | 30 | 27 | 7 | 30 | 53 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.23 |
| RP | Raymond, C.Raymond, Claude >> | 28 | 1965 | R | 6 | 52 | 0 | 4 | 1 | 3.60 | .286 | 1.18 | 8.2 | 2.4 | 5.4 | 85.0 | 77 | 36 | 34 | 8 | 23 | 51 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.91 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 47 | 0 | 1 | 1 | 2.06 | .246 | 0.98 | 6.0 | 2.8 | 6.9 | 48.0 | 32 | 12 | 11 | 4 | 15 | 37 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.48 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 6 | 0 | 2 | 1 | 7.88 | .351 | 1.63 | 13.5 | 1.1 | 1.1 | 8.0 | 12 | 7 | 7 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.75 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 43 | 0 | 5 | 1 | 3.35 | .301 | 1.29 | 8.8 | 2.9 | 8.3 | 40.1 | 39 | 15 | 15 | 5 | 13 | 37 | 0 | 28 | 4 | 0 | 0 | 0 | 1 | 3.75 |