| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 4 | 4 | 4.26 | .321 | 1.41 | 8.9 | 3.8 | 11.0 | 80.1 | 79 | 38 | 38 | 14 | 34 | 98 | 1 | 0 | 0 | 0 | 8 | 1 | 0 | 4.14 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 14 | 14 | 5 | 5 | 5.21 | .349 | 1.61 | 10.2 | 4.4 | 9.9 | 77.2 | 87 | 50 | 45 | 11 | 38 | 85 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.13 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 37 | 0 | 3 | 4 | 3.83 | .321 | 1.39 | 7.9 | 4.7 | 9.0 | 42.1 | 37 | 22 | 18 | 5 | 22 | 42 | 0 | 16 | 4 | 0 | 0 | 1 | 0 | 4.19 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 43 | 0 | 1 | 3 | 6.70 | .377 | 1.81 | 11.3 | 5.0 | 10.9 | 43.0 | 54 | 34 | 32 | 8 | 24 | 52 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 4.67 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 42 | 0 | 3 | 2 | 5.21 | .335 | 1.51 | 9.2 | 4.5 | 11.1 | 48.1 | 49 | 28 | 28 | 7 | 24 | 59 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.94 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 32 | 0 | 5 | 0 | 3.53 | .287 | 1.18 | 7.5 | 3.3 | 6.7 | 35.2 | 29 | 14 | 14 | 2 | 13 | 26 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.46 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 27 | 0 | 0 | 0 | 4.26 | .326 | 1.42 | 7.0 | 6.1 | 12.8 | 31.2 | 24 | 16 | 15 | 5 | 21 | 44 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.39 |