| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 29 | 29 | 11 | 8 | 5.50 | .312 | 1.33 | 10.5 | 1.5 | 7.0 | 170.1 | 199 | 111 | 104 | 27 | 28 | 133 | 3 | 0 | 0 | 1 | 12 | 5 | 5 | 4.08 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 27 | 27 | 7 | 11 | 6.29 | .354 | 1.62 | 10.6 | 4.0 | 5.1 | 156.0 | 183 | 114 | 109 | 23 | 69 | 89 | 1 | 0 | 0 | 1 | 6 | 5 | 4 | 5.20 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 70 | 0 | 4 | 4 | 4.48 | .287 | 1.18 | 6.8 | 3.9 | 7.4 | 86.1 | 65 | 45 | 43 | 10 | 37 | 71 | 0 | 33 | 4 | 0 | 0 | 2 | 0 | 4.22 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 71 | 0 | 5 | 2 | 3.76 | .297 | 1.24 | 6.9 | 4.3 | 9.1 | 83.2 | 64 | 36 | 35 | 6 | 40 | 84 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.43 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 54 | 0 | 2 | 2 | 3.17 | .298 | 1.26 | 7.8 | 3.7 | 10.2 | 59.2 | 51 | 21 | 21 | 8 | 24 | 67 | 0 | 3 | 0 | 0 | 0 | 1 | 6 | 3.76 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 56 | 0 | 9 | 0 | 4.38 | .351 | 1.58 | 8.8 | 5.5 | 9.3 | 72.0 | 70 | 36 | 35 | 9 | 44 | 74 | 0 | 1 | 0 | 0 | 0 | 3 | 5 | 4.53 |