| SP | Hamels, C.Hamels, Cole # >> | 29 | 2012 | L | 91 | 33 | 33 | 18 | 11 | 3.55 | .293 | 1.23 | 8.9 | 2.2 | 7.5 | 223.0 | 221 | 88 | 88 | 20 | 54 | 186 | 6 | 0 | 0 | 2 | 21 | 2 | 4 | 3.25 |
| SP | Lohse, K.Lohse, Kyle # >> | 35 | 2013 | R | 63 | 33 | 33 | 7 | 17 | 6.55 | .365 | 1.71 | 12.8 | 2.6 | 5.0 | 158.0 | 224 | 127 | 115 | 26 | 46 | 88 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 4.94 |
| SP | Pineda, M.Pineda, Michael >> | 32 | 2021 | R | 48 | 32 | 32 | 4 | 16 | 7.68 | .391 | 1.88 | 13.4 | 3.5 | 6.5 | 130.0 | 194 | 118 | 111 | 20 | 50 | 94 | 0 | 0 | 0 | 0 | 2 | 6 | 6 | 4.85 |
| RP | Foulke, K.Foulke, Keith † >> | 32 | 2004 | R | 92 | 95 | 0 | 8 | 0 | 3.04 | .292 | 1.21 | 8.3 | 2.7 | 7.4 | 121.1 | 111 | 44 | 41 | 14 | 36 | 99 | 0 | 5 | 3 | 0 | 0 | 3 | 7 | 3.83 |
| RP | Perdomo, L.Perdomo, Luis >> | 25 | 2009 | R | 27 | 72 | 0 | 5 | 7 | 5.11 | .365 | 1.70 | 9.8 | 5.6 | 5.1 | 100.1 | 109 | 60 | 57 | 10 | 62 | 57 | 0 | 5 | 4 | 0 | 0 | 2 | 7 | 5.08 |
| RP | Williams, M.Williams, Mike >> | 30 | 1999 | R | 16 | 75 | 0 | 3 | 2 | 3.83 | .341 | 1.53 | 9.1 | 4.7 | 10.0 | 82.1 | 83 | 37 | 35 | 6 | 43 | 91 | 0 | 4 | 5 | 0 | 0 | 2 | 7 | 3.38 |
| SP | Ostermueller, F.Ostermueller, Fritz >> | 32 | 1939 | L | 15 | 17 | 0 | 1 | 2 | 5.24 | .340 | 1.54 | 9.8 | 4.2 | 3.4 | 34.1 | 37 | 23 | 20 | 4 | 16 | 13 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.18 |