| SP | Clemens, R.Clemens, Roger >> | 43 | 2005 | R | 94 | 9 | 9 | 4 | 2 | 4.56 | .325 | 1.44 | 9.7 | 3.4 | 6.4 | 51.1 | 55 | 26 | 26 | 8 | 19 | 36 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.75 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 87 | 9 | 9 | 2 | 2 | 7.52 | .348 | 1.60 | 11.3 | 3.4 | 8.6 | 40.2 | 50 | 34 | 34 | 10 | 15 | 38 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.48 |
| SP | Lackey, J.Lackey, John >> | 29 | 2007 | R | 10 | 9 | 8 | 3 | 2 | 7.68 | .377 | 1.76 | 10.5 | 5.5 | 6.3 | 36.1 | 42 | 34 | 31 | 6 | 22 | 25 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 5.78 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 32 | 0 | 2 | 3 | 3.51 | .276 | 1.12 | 7.2 | 2.9 | 11.0 | 41.0 | 33 | 16 | 16 | 5 | 13 | 50 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 3.17 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 72 | 29 | 0 | 2 | 1 | 4.18 | .353 | 1.58 | 10.1 | 4.2 | 6.8 | 32.1 | 36 | 15 | 15 | 4 | 15 | 24 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.72 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 51 | 19 | 0 | 2 | 0 | 5.40 | .360 | 1.69 | 12.5 | 3.1 | 4.2 | 26.2 | 36 | 18 | 16 | 4 | 9 | 12 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.12 |
| CL | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 25 | 0 | 3 | 1 | 2.76 | .302 | 1.23 | 9.0 | 2.2 | 8.1 | 29.1 | 29 | 9 | 9 | 3 | 7 | 26 | 0 | 12 | 1 | 0 | 0 | 2 | 2 | 3.48 |