| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 21 | 21 | 10 | 5 | 3.36 | .280 | 1.12 | 7.6 | 2.5 | 9.1 | 150.0 | 126 | 60 | 56 | 19 | 42 | 151 | 6 | 0 | 0 | 3 | 13 | 7 | 0 | 3.61 |
| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 87 | 21 | 21 | 8 | 9 | 3.90 | .281 | 1.16 | 8.2 | 2.3 | 10.2 | 129.1 | 117 | 59 | 56 | 21 | 33 | 146 | 0 | 0 | 0 | 0 | 13 | 2 | 6 | 3.67 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 20 | 20 | 5 | 8 | 4.96 | .324 | 1.38 | 10.0 | 2.4 | 6.4 | 134.1 | 149 | 76 | 74 | 22 | 36 | 95 | 0 | 0 | 0 | 0 | 10 | 8 | 0 | 4.70 |
| SP | Clement, M.Clement, Matt >> | 28 | 2002 | R | 55 | 20 | 20 | 7 | 5 | 6.21 | .354 | 1.61 | 9.5 | 5.1 | 9.1 | 95.2 | 100 | 68 | 66 | 18 | 54 | 96 | 0 | 0 | 0 | 0 | 5 | 3 | 3 | 5.24 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 50 | 0 | 5 | 1 | 0.95 | .168 | 0.58 | 3.3 | 1.9 | 11.2 | 66.0 | 24 | 7 | 7 | 2 | 14 | 82 | 0 | 23 | 1 | 0 | 0 | 2 | 2 | 1.64 |
| RP | Soria, J.Soria, Joakim † >> | 24 | 2008 | R | 88 | 59 | 0 | 9 | 1 | 3.30 | .271 | 1.08 | 5.6 | 4.1 | 6.4 | 79.0 | 49 | 30 | 29 | 11 | 36 | 56 | 0 | 3 | 2 | 0 | 0 | 3 | 0 | 4.87 |
| RP | Wagner, B.Wagner, Billy >> | 32 | 2003 | L | 90 | 38 | 0 | 4 | 2 | 3.21 | .289 | 1.13 | 7.5 | 2.9 | 10.3 | 47.2 | 39 | 17 | 17 | 7 | 15 | 54 | 0 | 1 | 1 | 0 | 0 | 4 | 3 | 3.85 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 37 | 0 | 4 | 0 | 3.92 | .319 | 1.35 | 7.7 | 4.6 | 10.3 | 41.1 | 35 | 18 | 18 | 6 | 21 | 47 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 4.29 |