| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 9 | 9 | 1 | 3 | 5.21 | .299 | 1.25 | 8.7 | 2.5 | 9.2 | 57.0 | 55 | 34 | 33 | 11 | 16 | 58 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 4.42 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 80 | 9 | 9 | 5 | 2 | 4.70 | .321 | 1.40 | 7.6 | 5.1 | 8.8 | 53.2 | 45 | 28 | 28 | 6 | 30 | 52 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.26 |
| SP | Williams, W.Williams, Woody >> | 36 | 2002 | R | 80 | 7 | 7 | 3 | 2 | 6.38 | .325 | 1.42 | 10.8 | 2.3 | 3.3 | 36.2 | 43 | 26 | 26 | 7 | 9 | 13 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.64 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 70 | 8 | 8 | 4 | 2 | 4.44 | .319 | 1.37 | 10.2 | 2.3 | 6.2 | 52.2 | 59 | 27 | 26 | 7 | 13 | 36 | 1 | 0 | 0 | 0 | 4 | 2 | 1 | 4.23 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 19 | 0 | 1 | 0 | 1.66 | .261 | 1.06 | 6.4 | 3.4 | 9.4 | 21.2 | 15 | 4 | 4 | 2 | 8 | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.29 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 14 | 0 | 1 | 2 | 3.57 | .321 | 1.36 | 9.5 | 3.2 | 12.2 | 17.2 | 18 | 8 | 7 | 3 | 6 | 23 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 64 | 9 | 0 | 0 | 0 | 4.05 | .355 | 1.65 | 15.0 | 1.5 | 9.0 | 6.2 | 10 | 3 | 3 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.50 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 61 | 7 | 0 | 0 | 1 | 9.39 | .439 | 2.35 | 16.7 | 6.4 | 3.9 | 7.2 | 13 | 9 | 8 | 2 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |
| SP | Millwood, K.Millwood, Kevin >> | 28 | 2002 | R | 53 | 1 | 1 | 0 | 1 | 11.25 | .455 | 2.00 | 13.5 | 4.5 | 2.3 | 4.0 | 6 | 5 | 5 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 8.75 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 6 | 0 | 3 | 0 | 5.88 | .333 | 1.50 | 9.3 | 4.2 | 8.0 | 26.0 | 27 | 17 | 17 | 4 | 12 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.62 |