| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 94 | 26 | 26 | 10 | 10 | 4.39 | .308 | 1.32 | 8.6 | 3.3 | 5.9 | 149.2 | 143 | 79 | 73 | 22 | 54 | 97 | 6 | 0 | 0 | 0 | 12 | 3 | 6 | 4.77 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 27 | 26 | 7 | 12 | 4.67 | .290 | 1.22 | 8.4 | 2.7 | 8.6 | 146.1 | 136 | 77 | 76 | 26 | 43 | 139 | 4 | 0 | 0 | 1 | 10 | 0 | 3 | 4.29 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 25 | 25 | 8 | 6 | 3.41 | .283 | 1.16 | 7.7 | 2.8 | 4.3 | 142.2 | 121 | 62 | 54 | 7 | 44 | 68 | 2 | 0 | 0 | 2 | 13 | 4 | 1 | 3.70 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 20 | 19 | 4 | 5 | 5.02 | .337 | 1.52 | 9.6 | 4.1 | 5.3 | 86.0 | 92 | 53 | 48 | 16 | 39 | 51 | 0 | 0 | 0 | 0 | 5 | 0 | 2 | 5.59 |
| RP | Benitez, A.Benitez, Armando # >> | 32 | 2004 | R | 82 | 72 | 0 | 6 | 5 | 4.25 | .299 | 1.27 | 8.5 | 2.9 | 5.9 | 89.0 | 84 | 48 | 42 | 17 | 29 | 58 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 5.19 |
| SU | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 59 | 0 | 4 | 3 | 4.31 | .305 | 1.28 | 8.5 | 3.1 | 10.9 | 56.1 | 53 | 27 | 27 | 5 | 19 | 68 | 0 | 1 | 6 | 0 | 0 | 2 | 5 | 2.86 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 61 | 0 | 5 | 0 | 4.00 | .264 | 1.05 | 6.1 | 3.4 | 8.9 | 69.2 | 47 | 32 | 31 | 15 | 26 | 68 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.07 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 43 | 0 | 3 | 5 | 2.96 | .259 | 1.01 | 7.1 | 2.1 | 8.6 | 48.2 | 38 | 16 | 16 | 4 | 11 | 46 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 2.98 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 19 | 5 | 4 | 3 | 4.87 | .303 | 1.27 | 9.4 | 2.0 | 4.4 | 85.0 | 89 | 46 | 46 | 13 | 19 | 42 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 4.78 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 50 | 0 | 2 | 1 | 3.07 | .254 | 0.97 | 6.9 | 2.0 | 8.5 | 55.2 | 42 | 19 | 19 | 8 | 12 | 52 | 0 | 28 | 5 | 0 | 0 | 3 | 3 | 3.82 |