| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 22 | 22 | 12 | 5 | 3.94 | .310 | 1.32 | 7.6 | 4.3 | 9.4 | 146.1 | 124 | 65 | 64 | 24 | 69 | 152 | 0 | 0 | 0 | 0 | 12 | 4 | 4 | 4.55 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 21 | 21 | 10 | 8 | 4.54 | .312 | 1.35 | 8.7 | 3.5 | 6.8 | 140.2 | 136 | 71 | 71 | 20 | 54 | 105 | 1 | 0 | 0 | 1 | 10 | 1 | 2 | 4.54 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 21 | 21 | 8 | 6 | 5.78 | .332 | 1.47 | 10.2 | 3.1 | 7.2 | 127.2 | 144 | 82 | 82 | 30 | 44 | 101 | 0 | 0 | 0 | 0 | 8 | 2 | 2 | 5.57 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 21 | 20 | 10 | 5 | 3.76 | .270 | 1.09 | 7.1 | 2.8 | 8.3 | 134.0 | 105 | 56 | 56 | 18 | 41 | 123 | 1 | 0 | 0 | 1 | 13 | 3 | 2 | 3.90 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 95 | 43 | 0 | 3 | 4 | 4.43 | .299 | 1.23 | 7.0 | 4.3 | 11.0 | 40.2 | 31 | 20 | 20 | 5 | 19 | 49 | 0 | 27 | 5 | 0 | 0 | 2 | 1 | 3.75 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 44 | 0 | 0 | 0 | 2.20 | .246 | 0.96 | 5.5 | 3.1 | 8.4 | 49.0 | 30 | 13 | 12 | 6 | 17 | 46 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 55 | 0 | 2 | 4 | 3.88 | .324 | 1.37 | 9.1 | 3.3 | 12.3 | 62.2 | 63 | 31 | 27 | 8 | 23 | 85 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 3.24 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 40 | 0 | 3 | 3 | 3.50 | .294 | 1.23 | 7.6 | 3.5 | 9.0 | 46.1 | 39 | 18 | 18 | 9 | 18 | 46 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.78 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 29 | 0 | 4 | 0 | 3.76 | .303 | 1.28 | 6.9 | 4.7 | 7.1 | 38.1 | 29 | 19 | 16 | 6 | 20 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.13 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 4 | 0 | 1 | 0 | 5.06 | .304 | 1.13 | 9.0 | 1.8 | 12.6 | 5.1 | 5 | 4 | 3 | 3 | 1 | 7 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 9.20 |