| SP | deGrom, J.deGrom, Jacob † # $ >> | 33 | 2021 | R | 100 | 17 | 17 | 10 | 2 | 3.29 | .252 | 0.98 | 7.5 | 1.3 | 11.5 | 115.0 | 96 | 43 | 42 | 20 | 17 | 147 | 1 | 0 | 0 | 0 | 12 | 3 | 0 | 3.23 |
| SP | Kluber, C.Kluber, Corey $ >> | 31 | 2017 | R | 95 | 17 | 17 | 9 | 6 | 3.82 | .271 | 1.11 | 7.2 | 2.8 | 9.4 | 113.0 | 90 | 50 | 48 | 14 | 35 | 118 | 5 | 0 | 0 | 4 | 11 | 1 | 3 | 3.48 |
| SP | Fernandez, J.Fernandez, Jose † >> | 21 | 2013 | R | 82 | 16 | 16 | 9 | 1 | 2.07 | .282 | 1.16 | 5.9 | 4.6 | 9.3 | 108.2 | 71 | 25 | 25 | 6 | 55 | 112 | 0 | 0 | 0 | 0 | 11 | 2 | 1 | 3.23 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 14 | 14 | 7 | 3 | 4.42 | .309 | 1.34 | 9.4 | 2.8 | 9.3 | 91.2 | 95 | 46 | 45 | 18 | 28 | 94 | 2 | 0 | 0 | 0 | 8 | 0 | 0 | 4.43 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 42 | 0 | 4 | 2 | 1.92 | .232 | 0.91 | 5.8 | 2.4 | 9.0 | 56.1 | 36 | 14 | 12 | 3 | 15 | 56 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 2.50 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 32 | 0 | 0 | 4 | 5.73 | .336 | 1.52 | 8.2 | 5.5 | 8.5 | 33.0 | 30 | 22 | 21 | 5 | 20 | 31 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.91 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 24 | 0 | 2 | 3 | 4.20 | .280 | 1.17 | 6.6 | 3.9 | 8.1 | 30.0 | 22 | 18 | 14 | 5 | 13 | 27 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.67 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 78 | 14 | 0 | 0 | 0 | 4.38 | .288 | 1.22 | 8.3 | 3.0 | 12.0 | 12.1 | 11 | 6 | 6 | 4 | 4 | 16 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 5.67 |