| SP | Kluber, C.Kluber, Corey $ >> | 31 | 2017 | R | 95 | 36 | 36 | 11 | 16 | 4.35 | .293 | 1.22 | 8.3 | 2.8 | 8.8 | 233.2 | 214 | 118 | 113 | 37 | 72 | 228 | 6 | 0 | 0 | 2 | 19 | 5 | 3 | 4.10 |
| SP | Snell, B.Snell, Blake $$ >> | 25 | 2018 | L | 88 | 35 | 35 | 15 | 11 | 2.82 | .265 | 1.05 | 5.4 | 4.1 | 8.9 | 207.2 | 124 | 67 | 65 | 13 | 94 | 205 | 2 | 0 | 0 | 2 | 18 | 7 | 11 | 3.30 |
| SP | Ryan, N.Ryan, Nolan † $$ >> | 44 | 1991 | R | 80 | 34 | 34 | 18 | 7 | 3.48 | .292 | 1.21 | 7.2 | 3.7 | 8.1 | 222.1 | 178 | 89 | 86 | 28 | 91 | 201 | 2 | 0 | 0 | 1 | 22 | 6 | 9 | 4.14 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 79 | 33 | 33 | 13 | 11 | 4.47 | .294 | 1.22 | 8.1 | 3.0 | 7.0 | 219.1 | 196 | 112 | 109 | 35 | 72 | 170 | 5 | 0 | 0 | 1 | 16 | 6 | 5 | 4.59 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 57 | 31 | 31 | 12 | 10 | 4.18 | .307 | 1.30 | 8.1 | 3.7 | 9.6 | 178.2 | 160 | 84 | 83 | 17 | 73 | 189 | 1 | 0 | 0 | 0 | 19 | 4 | 3 | 3.42 |
| CL | Papelbon, J.Papelbon, Jonathan $$ >> | 27 | 2007 | R | 90 | 64 | 0 | 3 | 9 | 3.48 | .296 | 1.22 | 7.4 | 3.6 | 9.4 | 67.1 | 55 | 26 | 26 | 11 | 27 | 70 | 0 | 33 | 6 | 0 | 0 | 3 | 0 | 4.39 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 92 | 88 | 0 | 4 | 2 | 2.36 | .248 | 0.98 | 6.4 | 2.4 | 9.2 | 103.0 | 73 | 27 | 27 | 9 | 28 | 105 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.94 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 75 | 0 | 5 | 4 | 3.14 | .268 | 1.10 | 6.8 | 3.2 | 9.6 | 77.1 | 58 | 28 | 27 | 11 | 27 | 82 | 0 | 6 | 3 | 0 | 0 | 0 | 2 | 3.78 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 47 | 0 | 5 | 4 | 2.74 | .285 | 1.20 | 6.4 | 4.4 | 10.8 | 49.1 | 35 | 15 | 15 | 3 | 24 | 59 | 0 | 1 | 0 | 0 | 0 | 0 | 6 | 2.86 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 26 | 30 | 0 | 5 | 1 | 4.68 | .323 | 1.39 | 9.7 | 2.8 | 5.9 | 115.1 | 124 | 63 | 60 | 18 | 36 | 76 | 0 | 0 | 1 | 0 | 0 | 5 | 0 | 4.78 |
| RP | Dotel, O.Dotel, Octavio # >> | 29 | 2002 | R | 66 | 43 | 0 | 1 | 2 | 6.44 | .340 | 1.52 | 8.8 | 5.0 | 9.2 | 43.1 | 42 | 33 | 31 | 9 | 24 | 44 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.42 |