| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 36 | 36 | 23 | 6 | 3.32 | .295 | 1.25 | 7.7 | 3.6 | 8.7 | 249.2 | 212 | 94 | 92 | 19 | 99 | 240 | 2 | 0 | 0 | 2 | 24 | 3 | 5 | 3.29 |
| SP | Maddux, G.Maddux, Greg † # >> | 29 | 1995 | R | 90 | 34 | 34 | 24 | 5 | 3.26 | .258 | 1.03 | 7.4 | 1.9 | 5.8 | 262.2 | 216 | 101 | 95 | 32 | 54 | 168 | 14 | 0 | 0 | 2 | 20 | 4 | 4 | 3.97 |
| SP | Guidry, R.Guidry, Ron † >> | 28 | 1978 | L | 83 | 33 | 33 | 18 | 6 | 5.12 | .342 | 1.52 | 9.3 | 4.4 | 6.5 | 216.1 | 223 | 126 | 123 | 28 | 106 | 157 | 4 | 0 | 0 | 0 | 13 | 9 | 4 | 4.83 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 53 | 31 | 30 | 15 | 8 | 3.30 | .316 | 1.38 | 7.2 | 5.2 | 9.1 | 199.0 | 160 | 81 | 73 | 22 | 114 | 201 | 0 | 1 | 0 | 0 | 20 | 2 | 3 | 4.17 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 69 | 0 | 7 | 1 | 2.90 | .257 | 1.04 | 7.3 | 2.2 | 9.7 | 83.2 | 67 | 27 | 27 | 10 | 20 | 89 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 3.14 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 31 | 0 | 2 | 0 | 6.21 | .336 | 1.52 | 11.2 | 2.5 | 8.1 | 29.0 | 36 | 21 | 20 | 9 | 8 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.07 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 31 | 0 | 2 | 1 | 4.19 | .275 | 1.09 | 6.9 | 3.1 | 10.2 | 38.2 | 29 | 18 | 18 | 4 | 13 | 43 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.29 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 67 | 0 | 5 | 8 | 3.58 | .267 | 1.09 | 6.3 | 3.6 | 10.7 | 70.1 | 49 | 28 | 28 | 10 | 28 | 83 | 0 | 41 | 6 | 0 | 0 | 0 | 2 | 3.69 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 17 | 1 | 5 | 2 | 4.71 | .312 | 1.32 | 8.5 | 3.5 | 6.7 | 70.2 | 66 | 40 | 37 | 13 | 27 | 52 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 5.21 |