| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 5 | 5 | 2 | 2 | 3.04 | .266 | 1.05 | 6.2 | 3.5 | 4.8 | 26.2 | 18 | 10 | 9 | 4 | 10 | 14 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 5.19 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 5 | 5 | 2 | 0 | 3.41 | .246 | 0.98 | 6.4 | 2.6 | 4.4 | 31.2 | 22 | 12 | 12 | 1 | 9 | 15 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.32 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 5 | 5 | 3 | 0 | 4.28 | .311 | 1.32 | 7.0 | 5.0 | 4.0 | 27.1 | 21 | 14 | 13 | 4 | 15 | 12 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 5.81 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 13 | 0 | 0 | 0 | 4.40 | .328 | 1.47 | 7.1 | 6.4 | 8.4 | 14.1 | 11 | 7 | 7 | 1 | 10 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.21 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 14 | 0 | 1 | 0 | 4.15 | .297 | 1.27 | 10.1 | 2.3 | 11.3 | 8.2 | 9 | 4 | 4 | 2 | 2 | 10 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.50 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 10 | 0 | 1 | 1 | 0.73 | .159 | 0.57 | 3.0 | 2.3 | 11.3 | 12.1 | 4 | 1 | 1 | 1 | 3 | 15 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.33 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 57 | 6 | 0 | 1 | 0 | 4.15 | .409 | 2.08 | 11.3 | 9.0 | 18.0 | 4.1 | 5 | 2 | 2 | 1 | 4 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 5.25 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 32 | 13 | 0 | 0 | 1 | 6.43 | .276 | 1.14 | 6.4 | 3.9 | 7.7 | 7.0 | 5 | 5 | 5 | 2 | 3 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.29 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 61 | 3 | 0 | 0 | 0 | 9.82 | .313 | 1.36 | 15.0 | 0.0 | 15.0 | 3.2 | 5 | 4 | 4 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -0.33 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 5 | 0 | 1 | 0 | 1.69 | .256 | 1.03 | 4.5 | 5.4 | 5.4 | 10.2 | 5 | 2 | 2 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.90 |