| SP | Leonard, D.Leonard, Dutch $$ >> | 22 | 1914 | L | 91 | 33 | 33 | 14 | 9 | 2.97 | .276 | 1.12 | 7.3 | 2.9 | 4.1 | 175.2 | 141 | 66 | 58 | 16 | 56 | 80 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 4.30 |
| SP | Reulbach, E.Reulbach, Ed $$ >> | 24 | 1906 | R | 60 | 32 | 32 | 15 | 4 | 3.05 | .259 | 1.04 | 6.0 | 3.4 | 4.2 | 195.0 | 129 | 69 | 66 | 14 | 73 | 90 | 1 | 0 | 0 | 0 | 20 | 3 | 2 | 4.18 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 31 | 31 | 15 | 7 | 3.85 | .288 | 1.21 | 7.0 | 3.9 | 3.9 | 189.1 | 147 | 88 | 81 | 18 | 82 | 81 | 1 | 0 | 0 | 0 | 19 | 1 | 4 | 4.70 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 29 | 28 | 6 | 5 | 4.60 | .332 | 1.48 | 9.3 | 4.1 | 7.1 | 121.1 | 125 | 63 | 62 | 16 | 55 | 95 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 4.54 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 97 | 0 | 5 | 2 | 3.83 | .289 | 1.21 | 6.6 | 4.2 | 9.7 | 87.0 | 64 | 38 | 37 | 11 | 41 | 94 | 0 | 2 | 5 | 0 | 0 | 1 | 9 | 3.93 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 86 | 0 | 5 | 2 | 2.07 | .283 | 1.15 | 6.9 | 3.5 | 7.6 | 82.2 | 63 | 21 | 19 | 6 | 32 | 69 | 0 | 8 | 2 | 0 | 0 | 3 | 2 | 3.55 |
| RP | Urbina, U.Urbina, Ugueth † >> | 24 | 1998 | R | 59 | 57 | 0 | 7 | 4 | 3.29 | .297 | 1.25 | 7.1 | 4.2 | 8.1 | 52.0 | 41 | 19 | 19 | 5 | 24 | 47 | 0 | 10 | 5 | 0 | 0 | 1 | 4 | 3.88 |
| RP | Marmol, C.Marmol, Carlos † >> | 26 | 2008 | R | 71 | 44 | 0 | 4 | 2 | 1.68 | .241 | 0.95 | 5.1 | 3.6 | 6.8 | 48.1 | 27 | 9 | 9 | 2 | 19 | 36 | 0 | 12 | 0 | 0 | 0 | 0 | 0 | 3.23 |
| RP | LaRoche, D.LaRoche, Dave # >> | 28 | 1976 | L | 33 | 88 | 0 | 2 | 3 | 3.26 | .272 | 1.12 | 6.1 | 4.0 | 6.4 | 58.0 | 39 | 21 | 21 | 5 | 26 | 41 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.05 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 29 | 0 | 1 | 0 | 5.40 | .291 | 1.23 | 7.9 | 3.3 | 8.5 | 33.1 | 29 | 20 | 20 | 2 | 12 | 31 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.00 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 12 | 0 | 4 | 0 | 2.42 | .268 | 1.10 | 5.9 | 4.1 | 8.2 | 44.2 | 29 | 14 | 12 | 2 | 20 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.14 |