| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 23 | 23 | 11 | 4 | 2.78 | .247 | 0.97 | 5.5 | 3.2 | 5.5 | 126.1 | 77 | 42 | 39 | 11 | 45 | 77 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 4.03 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 73 | 22 | 22 | 11 | 4 | 2.77 | .273 | 1.10 | 5.8 | 4.2 | 7.6 | 123.2 | 79 | 41 | 38 | 6 | 57 | 104 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 3.41 |
| SP | Reulbach, E.Reulbach, Ed $ >> | 24 | 1906 | R | 61 | 22 | 22 | 12 | 4 | 3.28 | .292 | 1.23 | 7.1 | 4.0 | 4.2 | 134.1 | 106 | 52 | 49 | 11 | 59 | 62 | 0 | 0 | 0 | 0 | 14 | 1 | 3 | 4.49 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 71 | 0 | 3 | 2 | 3.36 | .307 | 1.31 | 7.4 | 4.5 | 8.5 | 56.1 | 46 | 22 | 21 | 5 | 28 | 53 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 3.82 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 58 | 0 | 4 | 1 | 1.68 | .222 | 0.84 | 3.6 | 4.1 | 9.2 | 53.2 | 21 | 10 | 10 | 3 | 24 | 54 | 0 | 2 | 4 | 0 | 0 | 1 | 6 | 3.11 |
| RP | Devine, J.Devine, Joey † >> | 25 | 2008 | R | 80 | 44 | 0 | 3 | 1 | 2.88 | .295 | 1.25 | 6.6 | 4.8 | 8.2 | 34.1 | 25 | 11 | 11 | 4 | 18 | 31 | 0 | 14 | 0 | 0 | 0 | 0 | 0 | 4.29 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 62 | 0 | 5 | 1 | 2.75 | .229 | 0.89 | 5.1 | 3.0 | 7.4 | 39.1 | 22 | 12 | 12 | 1 | 13 | 32 | 0 | 3 | 2 | 0 | 0 | 0 | 3 | 2.69 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 28 | 0 | 2 | 1 | 2.59 | .294 | 1.22 | 6.8 | 4.4 | 6.1 | 41.2 | 31 | 12 | 12 | 3 | 20 | 28 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 4.12 |