| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 64 | 23 | 16 | 4 | 7 | 6.21 | .330 | 1.46 | 9.9 | 3.3 | 8.4 | 113.0 | 124 | 80 | 78 | 26 | 41 | 105 | 0 | 1 | 0 | 0 | 6 | 2 | 4 | 5.27 |
| SP | Alexander, P.Alexander, Pete † # >> | 28 | 1915 | R | 88 | 32 | 32 | 21 | 7 | 3.23 | .257 | 1.02 | 6.8 | 2.3 | 5.2 | 234.1 | 177 | 85 | 84 | 22 | 61 | 134 | 3 | 0 | 0 | 1 | 23 | 5 | 2 | 3.92 |
| SP | Kershaw, C.Kershaw, Clayton † $ >> | 28 | 2016 | L | 99 | 33 | 32 | 17 | 11 | 2.83 | .253 | 1.00 | 7.5 | 1.5 | 7.8 | 257.2 | 214 | 81 | 81 | 22 | 44 | 223 | 15 | 1 | 0 | 2 | 22 | 4 | 4 | 2.94 |
| SP | McNally, D.McNally, Dave † $$ >> | 26 | 1968 | L | 96 | 31 | 31 | 15 | 7 | 3.15 | .267 | 1.09 | 7.3 | 2.5 | 4.8 | 240.1 | 194 | 85 | 84 | 13 | 67 | 128 | 8 | 0 | 0 | 3 | 20 | 2 | 5 | 3.50 |
| SP | Sale, C.Sale, Chris $$ >> | 29 | 2018 | L | 98 | 30 | 30 | 14 | 8 | 3.34 | .288 | 1.18 | 7.3 | 3.3 | 8.5 | 199.1 | 162 | 75 | 74 | 21 | 74 | 189 | 1 | 0 | 0 | 0 | 21 | 6 | 2 | 3.68 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 58 | 0 | 3 | 2 | 1.64 | .206 | 0.76 | 5.0 | 2.0 | 6.3 | 60.1 | 33 | 11 | 11 | 2 | 13 | 42 | 0 | 50 | 2 | 0 | 0 | 1 | 1 | 2.73 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 61 | 0 | 1 | 3 | 2.56 | .275 | 1.12 | 7.2 | 3.1 | 8.4 | 59.2 | 47 | 17 | 17 | 5 | 20 | 55 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 3.31 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 36 | 0 | 4 | 3 | 1.83 | .229 | 0.84 | 4.6 | 3.0 | 10.2 | 39.1 | 20 | 8 | 8 | 2 | 13 | 44 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2.56 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 24 | 0 | 3 | 2 | 0.94 | .259 | 1.01 | 6.8 | 2.6 | 7.7 | 28.2 | 21 | 3 | 3 | 1 | 8 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 17 | 0 | 2 | 0 | 1.88 | .258 | 1.04 | 6.4 | 3.0 | 6.4 | 24.0 | 17 | 6 | 5 | 2 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Henry, B.Henry, Bill # >> | 37 | 1964 | L | 69 | 77 | 0 | 7 | 1 | 3.60 | .257 | 1.04 | 6.3 | 3.1 | 4.3 | 50.0 | 35 | 20 | 20 | 1 | 17 | 24 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.32 |