| SP | Koufax, S.Koufax, Sandy # $$ >> | 30 | 1965 | L | 98 | 23 | 23 | 10 | 7 | 3.74 | .281 | 1.15 | 7.6 | 2.9 | 8.8 | 170.2 | 143 | 71 | 71 | 14 | 54 | 166 | 4 | 0 | 0 | 0 | 16 | 3 | 1 | 3.12 |
| SP | Maddux, G.Maddux, Greg # $$ >> | 29 | 1995 | R | 89 | 22 | 22 | 13 | 6 | 3.86 | .289 | 1.19 | 8.6 | 2.1 | 4.6 | 165.1 | 158 | 79 | 71 | 14 | 39 | 84 | 8 | 0 | 0 | 1 | 11 | 5 | 0 | 3.88 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 22 | 22 | 5 | 7 | 4.21 | .312 | 1.34 | 9.2 | 2.9 | 8.3 | 109.0 | 111 | 52 | 51 | 11 | 35 | 101 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 3.48 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 21 | 21 | 8 | 7 | 5.52 | .330 | 1.47 | 9.6 | 3.7 | 5.4 | 130.1 | 138 | 84 | 80 | 24 | 53 | 78 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 5.47 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 55 | 0 | 5 | 4 | 3.14 | .269 | 1.07 | 8.5 | 1.3 | 7.5 | 71.2 | 67 | 28 | 25 | 5 | 10 | 59 | 0 | 5 | 4 | 0 | 0 | 2 | 0 | 2.76 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 50 | 0 | 2 | 5 | 5.05 | .295 | 1.24 | 9.4 | 1.8 | 7.1 | 66.0 | 69 | 42 | 37 | 10 | 13 | 52 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 41 | 0 | 5 | 2 | 4.78 | .347 | 1.59 | 10.3 | 4.2 | 6.9 | 43.1 | 49 | 23 | 23 | 6 | 20 | 33 | 0 | 6 | 1 | 0 | 0 | 0 | 3 | 4.67 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 22 | 0 | 1 | 2 | 3.57 | .346 | 1.54 | 9.4 | 4.9 | 7.0 | 22.2 | 23 | 10 | 9 | 5 | 12 | 17 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 6.18 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 18 | 0 | 3 | 1 | 3.66 | .298 | 1.22 | 7.6 | 3.8 | 4.7 | 19.2 | 16 | 8 | 8 | 2 | 8 | 10 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.74 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |