| SP | Richard, J.Richard, J.R. $$ >> | 30 | 1980 | R | 90 | 23 | 23 | 11 | 5 | 3.19 | .287 | 1.17 | 7.2 | 3.4 | 7.8 | 138.1 | 110 | 50 | 49 | 11 | 52 | 120 | 0 | 0 | 0 | 0 | 13 | 5 | 3 | 3.54 |
| SP | Arrieta, J.Arrieta, Jake $$ >> | 29 | 2015 | R | 93 | 22 | 22 | 6 | 7 | 3.16 | .279 | 1.15 | 7.2 | 3.2 | 7.2 | 142.1 | 113 | 57 | 50 | 14 | 50 | 114 | 1 | 0 | 0 | 0 | 16 | 2 | 2 | 3.77 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 22 | 22 | 8 | 7 | 3.01 | .279 | 1.15 | 6.8 | 3.5 | 8.4 | 140.1 | 106 | 54 | 47 | 9 | 55 | 131 | 2 | 0 | 0 | 0 | 14 | 2 | 2 | 3.19 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 22 | 22 | 12 | 5 | 3.21 | .269 | 1.08 | 8.0 | 1.8 | 4.7 | 154.0 | 137 | 60 | 55 | 13 | 30 | 81 | 8 | 0 | 0 | 2 | 15 | 3 | 2 | 3.69 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 21 | 21 | 6 | 6 | 5.05 | .297 | 1.23 | 9.1 | 1.9 | 7.2 | 123.0 | 125 | 74 | 69 | 20 | 26 | 99 | 1 | 0 | 0 | 0 | 11 | 5 | 0 | 4.26 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 56 | 0 | 2 | 1 | 1.40 | .230 | 0.88 | 6.2 | 1.8 | 7.8 | 51.1 | 35 | 9 | 8 | 5 | 10 | 44 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.20 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 20 | 0 | 1 | 1 | 2.19 | .221 | 0.85 | 4.5 | 3.4 | 7.1 | 24.2 | 12 | 6 | 6 | 3 | 9 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 48 | 50 | 0 | 2 | 1 | 4.19 | .304 | 1.31 | 8.7 | 3.2 | 9.3 | 34.1 | 33 | 20 | 16 | 5 | 12 | 35 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.91 |