| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 93 | 15 | 15 | 3 | 6 | 3.62 | .284 | 1.16 | 8.3 | 2.2 | 9.3 | 112.0 | 103 | 47 | 45 | 10 | 27 | 116 | 3 | 0 | 0 | 1 | 9 | 3 | 0 | 2.89 |
| SP | Oswalt, R.Oswalt, Roy # >> | 24 | 2001 | R | 72 | 15 | 15 | 5 | 5 | 5.03 | .302 | 1.29 | 10.3 | 1.3 | 8.9 | 82.1 | 94 | 48 | 46 | 15 | 12 | 81 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 3.88 |
| SP | Shields, J.Shields, James >> | 26 | 2007 | R | 51 | 15 | 15 | 6 | 5 | 5.66 | .334 | 1.49 | 10.9 | 2.5 | 7.1 | 97.0 | 118 | 63 | 61 | 18 | 27 | 76 | 3 | 0 | 0 | 1 | 5 | 1 | 3 | 4.71 |
| SP | Harang, A.Harang, Aaron >> | 29 | 2007 | R | 50 | 14 | 14 | 3 | 9 | 8.10 | .380 | 1.83 | 12.6 | 3.9 | 6.7 | 73.1 | 102 | 73 | 66 | 17 | 32 | 54 | 0 | 0 | 0 | 0 | 3 | 1 | 4 | 5.90 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 93 | 37 | 0 | 2 | 2 | 2.72 | .278 | 1.14 | 8.2 | 2.1 | 8.4 | 59.2 | 54 | 19 | 18 | 4 | 14 | 55 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.78 |
| RP | Hoffman, T.Hoffman, Trevor >> | 42 | 2009 | R | 70 | 39 | 0 | 2 | 3 | 6.75 | .367 | 1.72 | 10.6 | 5.0 | 6.6 | 45.1 | 53 | 34 | 34 | 11 | 25 | 33 | 0 | 3 | 3 | 0 | 0 | 1 | 2 | 6.44 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 31 | 0 | 3 | 2 | 4.30 | .331 | 1.49 | 10.7 | 2.9 | 7.5 | 37.2 | 44 | 19 | 18 | 5 | 12 | 31 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.05 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 34 | 24 | 0 | 2 | 1 | 4.33 | .308 | 1.30 | 7.7 | 4.0 | 6.0 | 27.0 | 23 | 13 | 13 | 1 | 12 | 18 | 0 | 2 | 0 | 0 | 0 | 1 | 5 | 3.59 |
| RP | Hughes, P.Hughes, Philip >> | 23 | 2009 | R | 22 | 23 | 0 | 0 | 1 | 7.11 | .415 | 2.13 | 14.4 | 5.0 | 10.8 | 25.1 | 40 | 21 | 20 | 9 | 14 | 30 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.96 |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 24 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Patterson, J.Patterson, John >> | 27 | 2005 | R | 36 | 10 | 0 | 0 | 2 | 7.88 | .385 | 1.88 | 11.3 | 5.6 | 7.9 | 8.0 | 10 | 7 | 7 | 3 | 5 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 8.00 |