| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 97 | 15 | 15 | 7 | 4 | 5.06 | .311 | 1.32 | 8.8 | 3.2 | 7.6 | 99.2 | 97 | 57 | 56 | 17 | 35 | 84 | 2 | 0 | 0 | 0 | 7 | 3 | 0 | 4.69 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 79 | 15 | 15 | 4 | 8 | 5.50 | .323 | 1.38 | 9.4 | 3.0 | 6.9 | 90.0 | 94 | 55 | 55 | 11 | 30 | 69 | 0 | 0 | 0 | 0 | 7 | 5 | 1 | 4.22 |
| SP | Perez, O.Perez, Oliver >> | 23 | 2004 | L | 76 | 15 | 15 | 3 | 10 | 5.52 | .340 | 1.49 | 8.4 | 5.0 | 9.3 | 88.0 | 82 | 55 | 54 | 13 | 49 | 91 | 1 | 0 | 0 | 0 | 6 | 5 | 3 | 4.69 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 62 | 15 | 15 | 4 | 6 | 8.92 | .390 | 1.85 | 13.3 | 3.5 | 6.1 | 77.2 | 114 | 78 | 77 | 21 | 30 | 52 | 1 | 0 | 0 | 0 | 2 | 5 | 1 | 6.56 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 61 | 14 | 14 | 4 | 5 | 6.50 | .357 | 1.60 | 11.9 | 2.7 | 7.2 | 81.2 | 107 | 59 | 59 | 21 | 24 | 65 | 0 | 0 | 0 | 0 | 4 | 5 | 3 | 5.84 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 75 | 35 | 0 | 1 | 3 | 6.60 | .371 | 1.75 | 11.3 | 4.5 | 9.2 | 46.1 | 58 | 36 | 34 | 10 | 23 | 47 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.35 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 59 | 32 | 0 | 0 | 1 | 3.27 | .283 | 1.16 | 7.7 | 2.9 | 9.2 | 41.1 | 35 | 15 | 15 | 5 | 13 | 42 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.56 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 32 | 20 | 0 | 1 | 1 | 2.59 | .324 | 1.44 | 10.9 | 2.3 | 8.3 | 24.1 | 29 | 7 | 7 | 2 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Washburn, J.Washburn, Jarrod >> | 28 | 2002 | L | 34 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 48 | 2 | 0 | 1 | 0 | 3.18 | .320 | 1.41 | 12.6 | 1.8 | 14.4 | 5.2 | 7 | 2 | 2 | 0 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.40 |