| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 21 | 21 | 6 | 14 | 3.92 | .290 | 1.21 | 8.1 | 2.8 | 9.8 | 149.1 | 134 | 67 | 65 | 22 | 47 | 162 | 4 | 0 | 0 | 1 | 12 | 2 | 5 | 3.73 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 21 | 21 | 4 | 4 | 2.05 | .257 | 1.01 | 6.1 | 3.0 | 6.5 | 92.1 | 62 | 23 | 21 | 3 | 31 | 66 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 3.10 |
| SP | Maine, J.Maine, John # >> | 25 | 2006 | R | 70 | 20 | 20 | 8 | 5 | 4.48 | .284 | 1.18 | 7.7 | 2.9 | 7.8 | 126.2 | 108 | 64 | 63 | 26 | 41 | 109 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 4.98 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 51 | 20 | 20 | 11 | 3 | 4.39 | .318 | 1.38 | 9.4 | 3.0 | 6.7 | 123.0 | 129 | 65 | 60 | 15 | 41 | 92 | 0 | 0 | 0 | 0 | 10 | 2 | 4 | 4.14 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 20 | 20 | 6 | 9 | 5.28 | .312 | 1.34 | 9.2 | 2.9 | 5.7 | 129.2 | 132 | 76 | 76 | 23 | 42 | 82 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 5.07 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 71 | 48 | 0 | 4 | 1 | 3.39 | .271 | 1.12 | 6.3 | 3.9 | 9.0 | 63.2 | 44 | 24 | 24 | 6 | 27 | 63 | 0 | 2 | 2 | 0 | 0 | 0 | 4 | 3.52 |
| RP | Timlin, M.Timlin, Mike >> | 36 | 2002 | R | 50 | 50 | 0 | 1 | 2 | 4.26 | .301 | 1.28 | 9.1 | 2.4 | 6.0 | 63.1 | 64 | 33 | 30 | 16 | 17 | 42 | 0 | 10 | 3 | 0 | 0 | 1 | 2 | 5.83 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 41 | 34 | 0 | 3 | 3 | 4.35 | .310 | 1.30 | 6.9 | 4.8 | 6.0 | 39.1 | 30 | 19 | 19 | 5 | 21 | 26 | 0 | 7 | 1 | 0 | 0 | 2 | 1 | 5.10 |
| RP | Shields, S.Shields, Scot >> | 30 | 2005 | R | 32 | 28 | 0 | 2 | 2 | 6.23 | .345 | 1.52 | 9.6 | 4.2 | 9.9 | 30.1 | 32 | 22 | 21 | 3 | 14 | 33 | 0 | 2 | 0 | 0 | 0 | 2 | 1 | 3.70 |