| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 100 | 28 | 28 | 15 | 11 | 3.58 | .319 | 1.38 | 8.1 | 4.3 | 8.4 | 201.1 | 181 | 87 | 80 | 21 | 96 | 188 | 6 | 0 | 0 | 1 | 17 | 6 | 4 | 4.01 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 97 | 27 | 27 | 9 | 9 | 4.38 | .311 | 1.35 | 9.0 | 3.2 | 8.6 | 176.2 | 176 | 96 | 86 | 22 | 62 | 168 | 3 | 0 | 0 | 0 | 15 | 1 | 2 | 3.79 |
| SP | McKenzie, T.McKenzie, Triston # >> | 24 | 2022 | R | 78 | 27 | 27 | 12 | 4 | 4.84 | .298 | 1.26 | 9.3 | 2.1 | 7.6 | 169.1 | 175 | 96 | 91 | 29 | 39 | 142 | 1 | 0 | 0 | 0 | 15 | 2 | 3 | 4.28 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 60 | 25 | 25 | 7 | 9 | 5.34 | .343 | 1.54 | 8.3 | 5.6 | 9.7 | 146.2 | 135 | 90 | 87 | 13 | 91 | 158 | 1 | 0 | 0 | 1 | 11 | 4 | 13 | 3.95 |
| RP | Perez, O.Perez, Oliver † >> | 37 | 2018 | L | 93 | 67 | 0 | 6 | 0 | 2.05 | .269 | 1.06 | 5.8 | 3.7 | 8.0 | 88.0 | 57 | 20 | 20 | 8 | 36 | 78 | 0 | 10 | 4 | 0 | 0 | 4 | 1 | 3.77 |
| RP | Manship, J.Manship, Jeff >> | 30 | 2015 | R | 87 | 54 | 0 | 6 | 9 | 4.81 | .295 | 1.24 | 6.7 | 4.6 | 6.1 | 63.2 | 47 | 34 | 34 | 9 | 32 | 43 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 5.06 |
| RP | Clippard, T.Clippard, Tyler >> | 34 | 2019 | R | 79 | 36 | 0 | 3 | 1 | 4.06 | .285 | 1.19 | 8.3 | 2.7 | 8.0 | 37.2 | 34 | 17 | 17 | 6 | 11 | 33 | 0 | 5 | 2 | 0 | 0 | 0 | 2 | 4.22 |
| RP | Karinchak, J.Karinchak, James >> | 26 | 2022 | R | 49 | 21 | 0 | 1 | 1 | 5.18 | .324 | 1.44 | 6.8 | 6.4 | 14.6 | 24.1 | 18 | 14 | 14 | 4 | 17 | 39 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.04 |
| SP | Siebert, S.Siebert, Sonny >> | 31 | 1968 | R | 45 | 15 | 0 | 2 | 3 | 3.18 | .306 | 1.31 | 6.6 | 5.2 | 6.4 | 79.1 | 58 | 29 | 28 | 2 | 46 | 56 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.70 |