| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 90 | 34 | 34 | 9 | 16 | 4.71 | .311 | 1.35 | 9.0 | 3.2 | 8.3 | 164.1 | 164 | 99 | 86 | 25 | 58 | 151 | 1 | 0 | 0 | 1 | 14 | 1 | 5 | 4.22 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 76 | 33 | 33 | 12 | 9 | 4.16 | .299 | 1.26 | 9.3 | 2.1 | 9.4 | 158.0 | 163 | 74 | 73 | 23 | 36 | 165 | 0 | 0 | 0 | 0 | 16 | 3 | 2 | 3.54 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 74 | 31 | 31 | 10 | 9 | 4.59 | .311 | 1.34 | 7.9 | 4.2 | 7.9 | 162.2 | 142 | 91 | 83 | 13 | 76 | 143 | 0 | 0 | 0 | 0 | 13 | 2 | 10 | 3.72 |
| SP | Wilson, S.Wilson, Steven >> | 27 | 2022 | R | 71 | 29 | 29 | 0 | 3 | 6.55 | .368 | 1.73 | 10.0 | 5.5 | 7.8 | 44.0 | 49 | 34 | 32 | 4 | 27 | 38 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.36 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 94 | 84 | 0 | 8 | 3 | 3.83 | .302 | 1.28 | 7.5 | 4.0 | 9.1 | 110.1 | 92 | 48 | 47 | 12 | 49 | 111 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.79 |
| RP | Meredith, C.Meredith, Cla >> | 23 | 2006 | R | 87 | 85 | 0 | 11 | 3 | 2.97 | .256 | 1.03 | 7.9 | 1.3 | 5.6 | 115.0 | 101 | 40 | 38 | 13 | 17 | 71 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 3.70 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 82 | 73 | 0 | 4 | 5 | 2.09 | .267 | 1.07 | 7.5 | 2.2 | 8.9 | 99.0 | 82 | 24 | 23 | 6 | 24 | 98 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 2.60 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 77 | 64 | 0 | 6 | 1 | 4.20 | .330 | 1.46 | 10.0 | 3.2 | 9.4 | 64.1 | 71 | 36 | 30 | 6 | 23 | 67 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.25 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 74 | 54 | 0 | 4 | 3 | 2.38 | .317 | 1.38 | 7.1 | 5.5 | 9.0 | 56.2 | 44 | 23 | 15 | 3 | 34 | 56 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 3.57 |
| SU | Street, H.Street, Huston >> | 29 | 2012 | R | 98 | 56 | 0 | 0 | 0 | 2.86 | .280 | 1.16 | 6.1 | 4.5 | 10.1 | 56.2 | 38 | 21 | 18 | 3 | 28 | 63 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 2.95 |
| RP | Lamet, D.Lamet, Dinelson # >> | 27 | 2020 | R | 85 | 53 | 0 | 10 | 2 | 4.57 | .320 | 1.38 | 7.4 | 5.0 | 8.8 | 108.1 | 89 | 59 | 55 | 16 | 60 | 105 | 0 | 1 | 0 | 0 | 0 | 4 | 4 | 4.76 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 60 | 0 | 3 | 2 | 1.07 | .199 | 0.73 | 3.5 | 3.1 | 8.1 | 59.0 | 23 | 7 | 7 | 4 | 20 | 53 | 0 | 42 | 3 | 0 | 0 | 1 | 0 | 3.15 |