| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 58 | 23 | 23 | 12 | 6 | 3.62 | .309 | 1.34 | 8.4 | 3.6 | 5.6 | 149.0 | 139 | 61 | 60 | 14 | 60 | 93 | 2 | 0 | 0 | 2 | 13 | 1 | 4 | 4.20 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 47 | 23 | 22 | 6 | 14 | 4.06 | .312 | 1.35 | 9.1 | 3.1 | 4.9 | 124.0 | 125 | 63 | 56 | 13 | 43 | 68 | 0 | 1 | 0 | 0 | 11 | 1 | 0 | 4.33 |
| SP | Harden, R.Harden, Rich >> | 24 | 2005 | R | 51 | 21 | 21 | 2 | 12 | 6.41 | .348 | 1.57 | 10.4 | 3.7 | 6.9 | 87.0 | 101 | 67 | 62 | 15 | 36 | 67 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 5.01 |
| SP | Moscoso, G.Moscoso, Guillermo >> | 27 | 2011 | R | 35 | 21 | 20 | 4 | 11 | 4.70 | .329 | 1.46 | 9.7 | 3.6 | 5.3 | 95.2 | 102 | 53 | 50 | 15 | 38 | 56 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 5.11 |
| CL | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 50 | 0 | 3 | 6 | 3.95 | .296 | 1.26 | 7.3 | 4.1 | 8.4 | 57.0 | 46 | 25 | 25 | 4 | 26 | 53 | 0 | 22 | 3 | 0 | 0 | 0 | 0 | 3.42 |
| SU | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 69 | 52 | 0 | 0 | 3 | 3.63 | .278 | 1.12 | 6.2 | 3.9 | 9.0 | 57.0 | 39 | 23 | 23 | 7 | 25 | 57 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 4.02 |
| RP | Abad, F.Abad, Fernando >> | 28 | 2014 | L | 65 | 57 | 0 | 3 | 2 | 3.35 | .292 | 1.21 | 7.3 | 3.6 | 7.7 | 75.1 | 61 | 30 | 28 | 10 | 30 | 64 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.31 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 54 | 0 | 5 | 0 | 4.55 | .317 | 1.37 | 7.9 | 4.6 | 8.7 | 63.1 | 55 | 34 | 32 | 5 | 32 | 61 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Doolittle, S.Doolittle, Sean >> | 29 | 2016 | L | 27 | 45 | 0 | 3 | 2 | 3.14 | .265 | 1.06 | 7.4 | 2.2 | 9.5 | 57.1 | 47 | 23 | 20 | 5 | 14 | 60 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.82 |
| RP | Blevins, J.Blevins, Jerry >> | 30 | 2013 | L | 26 | 41 | 0 | 0 | 0 | 4.24 | .300 | 1.29 | 8.0 | 3.7 | 6.3 | 46.2 | 41 | 23 | 22 | 9 | 19 | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.39 |