| SP | Schilling, C.Schilling, Curt >> | 26 | 1992 | R | 69 | 33 | 33 | 8 | 7 | 4.16 | .299 | 1.27 | 8.4 | 3.1 | 5.5 | 155.2 | 145 | 73 | 72 | 15 | 53 | 94 | 0 | 0 | 0 | 0 | 13 | 1 | 0 | 4.09 |
| SP | Carlton, S.Carlton, Steve # >> | 37 | 1981 | L | 58 | 33 | 33 | 10 | 8 | 4.11 | .315 | 1.36 | 9.5 | 2.7 | 7.0 | 186.0 | 197 | 86 | 85 | 23 | 56 | 144 | 2 | 0 | 0 | 1 | 17 | 4 | 8 | 4.03 |
| SP | Sparks, T.Sparks, Tully # >> | 33 | 1907 | R | 57 | 32 | 32 | 8 | 12 | 4.36 | .290 | 1.20 | 8.6 | 2.2 | 4.1 | 173.1 | 166 | 85 | 84 | 21 | 42 | 78 | 3 | 0 | 0 | 0 | 13 | 4 | 0 | 4.47 |
| SP | Meadows, L.Meadows, Lee >> | 25 | 1919 | R | 50 | 32 | 29 | 8 | 17 | 4.74 | .322 | 1.40 | 9.0 | 3.6 | 4.5 | 161.1 | 161 | 88 | 85 | 19 | 65 | 80 | 4 | 0 | 0 | 0 | 13 | 4 | 4 | 4.83 |
| SP | Rixey, E.Rixey, Eppa # >> | 25 | 1916 | L | 49 | 31 | 31 | 9 | 10 | 4.88 | .319 | 1.39 | 9.7 | 2.9 | 4.9 | 166.0 | 178 | 93 | 90 | 15 | 53 | 91 | 3 | 0 | 0 | 1 | 12 | 2 | 3 | 4.07 |
| RP | Strahm, M.Strahm, Matt >> | 32 | 2024 | L | 92 | 87 | 0 | 7 | 1 | 2.86 | .243 | 0.92 | 6.0 | 2.3 | 9.9 | 97.2 | 65 | 32 | 31 | 9 | 25 | 107 | 0 | 1 | 2 | 0 | 0 | 4 | 2 | 2.90 |
| RP | Hoffman, J.Hoffman, Jeff >> | 31 | 2024 | R | 56 | 78 | 0 | 5 | 2 | 2.35 | .269 | 1.09 | 6.9 | 3.0 | 9.1 | 84.1 | 64 | 27 | 22 | 9 | 28 | 85 | 0 | 1 | 2 | 0 | 0 | 1 | 4 | 3.40 |
| RP | Farrell, T.Farrell, Turk >> | 33 | 1967 | R | 39 | 64 | 0 | 11 | 5 | 3.00 | .266 | 1.07 | 7.9 | 1.7 | 5.4 | 105.0 | 92 | 37 | 35 | 9 | 20 | 63 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 3.54 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 35 | 2015 | R | 44 | 39 | 0 | 3 | 1 | 5.86 | .333 | 1.47 | 9.5 | 3.9 | 8.5 | 35.1 | 37 | 23 | 23 | 4 | 15 | 33 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.97 |
| CL | Wagner, B.Wagner, Billy † >> | 34 | 2005 | L | 81 | 62 | 0 | 2 | 2 | 3.48 | .271 | 1.11 | 7.3 | 2.8 | 8.6 | 62.0 | 50 | 24 | 24 | 6 | 19 | 59 | 0 | 39 | 8 | 0 | 0 | 0 | 5 | 3.27 |