| SP | Martinez, P.Martinez, Pedro # $ >> | 29 | 2000 | R | 100 | 12 | 12 | 4 | 4 | 4.92 | .310 | 1.34 | 9.2 | 2.8 | 9.2 | 86.0 | 88 | 50 | 47 | 11 | 27 | 88 | 2 | 0 | 0 | 0 | 4 | 1 | 1 | 3.59 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 12 | 12 | 5 | 5 | 4.43 | .333 | 1.49 | 10.2 | 3.2 | 7.9 | 81.1 | 92 | 48 | 40 | 13 | 29 | 71 | 2 | 0 | 0 | 0 | 5 | 1 | 2 | 4.44 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 12 | 12 | 3 | 5 | 4.87 | .331 | 1.47 | 10.2 | 3.1 | 4.9 | 85.0 | 96 | 50 | 46 | 7 | 29 | 46 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 4.05 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 12 | 12 | 4 | 6 | 5.13 | .333 | 1.48 | 9.3 | 4.0 | 8.2 | 86.0 | 89 | 51 | 49 | 17 | 38 | 78 | 2 | 0 | 0 | 0 | 5 | 2 | 1 | 5.15 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 11 | 11 | 4 | 3 | 5.32 | .320 | 1.40 | 9.8 | 2.8 | 5.5 | 64.1 | 70 | 39 | 38 | 9 | 20 | 39 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.59 |
| RP | Eckersley, D.Eckersley, Dennis $ >> | 36 | 1990 | R | 88 | 31 | 0 | 2 | 1 | 4.54 | .324 | 1.41 | 10.8 | 2.1 | 9.0 | 39.2 | 47 | 21 | 20 | 4 | 9 | 39 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 13 | 0 | 1 | 0 | 3.18 | .239 | 0.94 | 5.8 | 2.6 | 8.5 | 17.0 | 11 | 11 | 6 | 4 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.06 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 12 | 0 | 2 | 1 | 3.27 | .327 | 1.36 | 9.0 | 3.3 | 13.9 | 11.0 | 11 | 6 | 4 | 1 | 4 | 17 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2.45 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 7 | 0 | 1 | 0 | 4.70 | .343 | 1.43 | 9.0 | 5.1 | 12.9 | 7.2 | 7 | 4 | 4 | 1 | 4 | 10 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.14 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 8 | 0 | 1 | 0 | 6.75 | .333 | 1.35 | 7.5 | 6.0 | 13.5 | 6.2 | 5 | 5 | 5 | 2 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Chapman, A.Chapman, Aroldis $$ >> | 26 | 2014 | L | 94 | 22 | 0 | 1 | 2 | 1.14 | .276 | 1.14 | 4.7 | 5.9 | 10.6 | 23.2 | 12 | 3 | 3 | 2 | 15 | 27 | 0 | 10 | 1 | 0 | 0 | 0 | 1 | 3.74 |