| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 14 | 11 | 3.81 | .292 | 1.23 | 8.4 | 2.7 | 8.1 | 210.0 | 195 | 96 | 89 | 18 | 63 | 189 | 4 | 0 | 0 | 1 | 14 | 2 | 2 | 3.24 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 27 | 27 | 10 | 10 | 3.77 | .294 | 1.23 | 8.9 | 2.2 | 4.0 | 198.0 | 195 | 91 | 83 | 20 | 49 | 87 | 8 | 0 | 0 | 2 | 16 | 3 | 2 | 4.22 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 27 | 27 | 9 | 14 | 5.77 | .349 | 1.60 | 11.2 | 3.2 | 7.1 | 184.0 | 229 | 129 | 118 | 32 | 65 | 145 | 3 | 0 | 0 | 0 | 9 | 2 | 6 | 4.78 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 72 | 0 | 2 | 6 | 3.73 | .289 | 1.19 | 8.1 | 2.6 | 9.8 | 89.1 | 80 | 44 | 37 | 7 | 26 | 97 | 0 | 10 | 7 | 0 | 0 | 3 | 0 | 2.82 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 58 | 0 | 4 | 4 | 4.73 | .286 | 1.20 | 9.0 | 1.9 | 6.9 | 72.1 | 72 | 39 | 38 | 10 | 15 | 55 | 0 | 10 | 5 | 0 | 0 | 0 | 0 | 3.90 |
| RP | Zimmerman, J.Zimmerman, Jeff # >> | 27 | 1999 | R | 70 | 47 | 0 | 2 | 5 | 5.24 | .353 | 1.59 | 9.2 | 5.3 | 6.1 | 44.2 | 45 | 26 | 26 | 5 | 26 | 30 | 0 | 6 | 3 | 0 | 0 | 2 | 1 | 5.02 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 62 | 23 | 0 | 1 | 2 | 8.07 | .356 | 1.66 | 9.6 | 5.3 | 5.6 | 29.0 | 31 | 26 | 26 | 6 | 17 | 18 | 0 | 1 | 1 | 0 | 0 | 0 | 4 | 6.21 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 21 | 0 | 2 | 0 | 4.96 | .324 | 1.41 | 9.8 | 3.1 | 9.0 | 32.2 | 35 | 18 | 18 | 5 | 11 | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.16 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 3 | 0 | 0 | 1 | 15.43 | .548 | 3.64 | 31.5 | 6.8 | 4.5 | 4.2 | 14 | 8 | 8 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.25 |