| SP | Arrieta, J.Arrieta, Jake $$ >> | 29 | 2015 | R | 95 | 10 | 10 | 5 | 3 | 3.52 | .273 | 1.05 | 7.3 | 2.1 | 7.7 | 64.0 | 52 | 27 | 25 | 7 | 15 | 55 | 1 | 0 | 0 | 0 | 6 | 5 | 1 | 3.64 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 75 | 10 | 10 | 2 | 1 | 4.56 | .314 | 1.33 | 10.0 | 2.1 | 12.6 | 47.1 | 52 | 24 | 24 | 10 | 11 | 66 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 3.79 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 68 | 10 | 10 | 4 | 3 | 3.51 | .278 | 1.16 | 7.0 | 3.5 | 7.4 | 66.2 | 51 | 31 | 26 | 7 | 26 | 54 | 2 | 0 | 0 | 0 | 5 | 0 | 1 | 3.92 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 68 | 10 | 9 | 0 | 8 | 9.25 | .397 | 1.97 | 12.5 | 5.3 | 7.8 | 36.0 | 50 | 37 | 37 | 7 | 21 | 31 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 5.56 |
| CL | Jansen, K.Jansen, Kenley $$ >> | 28 | 2016 | R | 96 | 23 | 0 | 1 | 0 | 2.66 | .276 | 1.14 | 6.7 | 3.9 | 7.8 | 23.2 | 17 | 7 | 7 | 1 | 10 | 20 | 0 | 13 | 0 | 0 | 0 | 0 | 0 | 3.13 |
| SU | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 21 | 0 | 0 | 1 | 6.53 | .347 | 1.60 | 9.0 | 5.9 | 9.5 | 20.2 | 20 | 15 | 15 | 5 | 13 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.10 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 26 | 0 | 3 | 0 | 4.19 | .299 | 1.28 | 8.2 | 3.4 | 9.3 | 34.1 | 31 | 20 | 16 | 7 | 13 | 35 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.76 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 25 | 0 | 2 | 1 | 3.99 | .296 | 1.26 | 8.1 | 3.4 | 9.9 | 29.1 | 26 | 13 | 13 | 8 | 11 | 32 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.52 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 21 | 0 | 3 | 1 | 4.44 | .331 | 1.41 | 9.7 | 3.1 | 10.0 | 26.1 | 28 | 13 | 13 | 6 | 9 | 29 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 5.04 |