| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 10 | 10 | 3 | 6 | 3.44 | .281 | 1.15 | 7.2 | 3.2 | 6.0 | 73.1 | 58 | 28 | 28 | 9 | 26 | 49 | 2 | 0 | 0 | 0 | 6 | 2 | 0 | 4.41 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 76 | 10 | 10 | 5 | 3 | 2.87 | .279 | 1.14 | 6.8 | 3.5 | 5.6 | 69.0 | 52 | 24 | 22 | 7 | 27 | 43 | 1 | 0 | 0 | 0 | 7 | 1 | 0 | 4.29 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 10 | 10 | 7 | 3 | 3.35 | .264 | 1.04 | 7.0 | 2.4 | 6.8 | 75.1 | 58 | 32 | 28 | 7 | 20 | 57 | 1 | 0 | 0 | 0 | 7 | 3 | 1 | 3.61 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 74 | 9 | 9 | 4 | 2 | 3.98 | .309 | 1.29 | 9.2 | 2.5 | 7.0 | 54.1 | 55 | 24 | 24 | 5 | 15 | 42 | 1 | 0 | 0 | 0 | 5 | 3 | 0 | 3.65 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 18 | 0 | 0 | 2 | 1.62 | .231 | 0.90 | 5.1 | 3.4 | 8.4 | 16.2 | 9 | 3 | 3 | 0 | 6 | 15 | 0 | 14 | 1 | 0 | 0 | 0 | 0 | 2.25 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 19 | 0 | 1 | 1 | 1.40 | .216 | 0.83 | 4.7 | 2.8 | 8.5 | 19.1 | 10 | 3 | 3 | 1 | 6 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.74 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 7 | 0 | 0 | 0 | 7.36 | .333 | 1.50 | 12.9 | 1.3 | 9.0 | 7.1 | 10 | 6 | 6 | 3 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 71 | 8 | 0 | 0 | 0 | 0.84 | .158 | 0.56 | 3.6 | 1.8 | 8.1 | 10.2 | 4 | 1 | 1 | 0 | 2 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.80 |