| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 38 | 38 | 19 | 13 | 3.45 | .290 | 1.20 | 7.9 | 2.9 | 6.7 | 271.1 | 238 | 108 | 104 | 32 | 87 | 203 | 3 | 0 | 0 | 0 | 25 | 7 | 6 | 4.08 |
| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 88 | 34 | 34 | 14 | 8 | 3.27 | .293 | 1.22 | 6.7 | 4.4 | 9.5 | 200.2 | 148 | 75 | 73 | 18 | 97 | 212 | 0 | 0 | 0 | 0 | 17 | 4 | 10 | 3.57 |
| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 90 | 34 | 34 | 18 | 10 | 3.64 | .279 | 1.13 | 7.7 | 2.5 | 6.6 | 247.1 | 212 | 106 | 100 | 26 | 68 | 181 | 5 | 0 | 0 | 0 | 23 | 7 | 7 | 3.81 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 34 | 34 | 13 | 12 | 3.82 | .290 | 1.22 | 7.7 | 3.3 | 6.2 | 235.1 | 202 | 106 | 100 | 29 | 86 | 162 | 3 | 0 | 0 | 2 | 18 | 1 | 7 | 4.34 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 30 | 29 | 11 | 11 | 4.82 | .310 | 1.32 | 9.2 | 2.7 | 7.1 | 164.1 | 168 | 91 | 88 | 23 | 49 | 130 | 1 | 1 | 0 | 0 | 16 | 4 | 3 | 4.21 |
| CL | Street, H.Street, Huston † $$ >> | 29 | 2012 | R | 95 | 71 | 0 | 4 | 8 | 2.38 | .250 | 0.99 | 5.1 | 3.8 | 10.3 | 72.0 | 41 | 19 | 19 | 3 | 30 | 82 | 0 | 43 | 3 | 0 | 0 | 1 | 0 | 2.56 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 85 | 0 | 8 | 2 | 2.91 | .284 | 1.14 | 7.5 | 2.8 | 8.8 | 92.2 | 77 | 32 | 30 | 8 | 29 | 90 | 0 | 3 | 1 | 0 | 0 | 4 | 3 | 3.25 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 35 | 0 | 2 | 1 | 3.03 | .284 | 1.16 | 8.8 | 1.9 | 10.2 | 38.2 | 37 | 14 | 13 | 7 | 8 | 43 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.84 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 36 | 0 | 2 | 1 | 3.35 | .288 | 1.21 | 6.8 | 4.3 | 11.0 | 40.1 | 30 | 16 | 15 | 2 | 19 | 49 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.63 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 72 | 15 | 4 | 3 | 2 | 4.33 | .318 | 1.40 | 9.5 | 3.2 | 6.6 | 68.2 | 72 | 38 | 33 | 9 | 24 | 50 | 0 | 0 | 1 | 0 | 3 | 0 | 1 | 4.31 |