| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 23 | 23 | 12 | 7 | 3.95 | .306 | 1.30 | 9.8 | 2.0 | 8.3 | 159.2 | 173 | 70 | 70 | 22 | 35 | 146 | 5 | 0 | 0 | 1 | 15 | 3 | 0 | 3.68 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 86 | 22 | 22 | 12 | 4 | 3.89 | .288 | 1.20 | 8.1 | 2.7 | 7.1 | 169.0 | 152 | 78 | 73 | 25 | 51 | 134 | 8 | 0 | 0 | 0 | 13 | 2 | 5 | 4.28 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 73 | 22 | 22 | 12 | 4 | 5.08 | .352 | 1.61 | 10.2 | 4.3 | 6.4 | 127.2 | 144 | 73 | 72 | 20 | 61 | 91 | 0 | 0 | 0 | 0 | 10 | 3 | 4 | 5.13 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 56 | 0 | 3 | 4 | 3.67 | .272 | 1.09 | 6.2 | 3.7 | 9.8 | 68.2 | 47 | 28 | 28 | 7 | 28 | 74 | 0 | 8 | 2 | 0 | 0 | 2 | 4 | 3.49 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 43 | 0 | 2 | 3 | 2.98 | .295 | 1.24 | 7.4 | 3.8 | 10.2 | 45.1 | 37 | 17 | 15 | 3 | 19 | 51 | 0 | 5 | 4 | 0 | 0 | 1 | 2 | 2.93 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 83 | 25 | 0 | 3 | 0 | 4.33 | .331 | 1.44 | 9.3 | 3.7 | 6.7 | 27.0 | 28 | 13 | 13 | 4 | 11 | 20 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 4.78 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 76 | 9 | 0 | 0 | 1 | 5.59 | .256 | 1.03 | 7.0 | 3.0 | 7.0 | 9.2 | 7 | 6 | 6 | 1 | 3 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.89 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 75 | 8 | 0 | 0 | 0 | 6.14 | .389 | 1.91 | 9.0 | 9.0 | 9.0 | 7.1 | 7 | 6 | 5 | 2 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.71 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 55 | 14 | 0 | 3 | 2 | 5.73 | .348 | 1.56 | 10.9 | 3.2 | 6.4 | 70.2 | 85 | 47 | 45 | 12 | 25 | 50 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.00 |