| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 9 | 9 | 3 | 5 | 3.24 | .272 | 1.11 | 7.3 | 2.8 | 6.6 | 72.1 | 58 | 26 | 26 | 8 | 22 | 53 | 1 | 0 | 0 | 1 | 6 | 1 | 2 | 3.93 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 85 | 9 | 9 | 3 | 5 | 4.76 | .332 | 1.44 | 11.2 | 1.9 | 5.8 | 62.1 | 77 | 34 | 33 | 8 | 13 | 40 | 2 | 0 | 0 | 0 | 5 | 3 | 0 | 4.16 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 8 | 8 | 2 | 4 | 4.34 | .310 | 1.34 | 9.6 | 2.5 | 6.8 | 58.0 | 62 | 36 | 28 | 6 | 16 | 44 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.66 |
| SP | Santana, E.Santana, Ervin # >> | 25 | 2008 | R | 55 | 8 | 8 | 2 | 5 | 6.37 | .361 | 1.68 | 11.5 | 3.7 | 8.0 | 53.2 | 68 | 38 | 38 | 15 | 22 | 47 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 6.21 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 8 | 8 | 3 | 4 | 4.94 | .320 | 1.37 | 9.5 | 2.8 | 7.2 | 51.0 | 54 | 28 | 28 | 6 | 16 | 41 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 3.98 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 96 | 27 | 0 | 0 | 2 | 6.04 | .402 | 1.97 | 12.3 | 5.7 | 11.9 | 22.1 | 30 | 15 | 15 | 2 | 14 | 29 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.59 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 63 | 15 | 0 | 0 | 1 | 1.10 | .246 | 0.98 | 5.6 | 3.4 | 7.3 | 16.1 | 10 | 2 | 2 | 1 | 6 | 13 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 28 | 2002 | R | 48 | 12 | 0 | 1 | 0 | 4.73 | .245 | 0.98 | 7.6 | 1.4 | 6.9 | 13.1 | 11 | 7 | 7 | 2 | 2 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.92 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 38 | 7 | 0 | 0 | 0 | 8.64 | .405 | 1.92 | 10.1 | 7.9 | 5.6 | 8.1 | 9 | 8 | 8 | 1 | 7 | 5 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 6.38 |
| RP | Stewart, S.Stewart, Scott >> | 27 | 2002 | L | 28 | 8 | 0 | 1 | 0 | 9.82 | .421 | 2.05 | 12.9 | 6.4 | 11.6 | 7.1 | 10 | 8 | 8 | 3 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.57 |