| SP | Santana, J.Santana, Johan † $$ >> | 25 | 2004 | L | 100 | 28 | 28 | 13 | 10 | 4.10 | .299 | 1.24 | 8.1 | 3.0 | 9.0 | 189.0 | 171 | 87 | 86 | 27 | 64 | 189 | 3 | 0 | 0 | 3 | 17 | 7 | 2 | 3.98 |
| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 87 | 27 | 27 | 6 | 10 | 5.18 | .344 | 1.54 | 10.6 | 3.3 | 8.7 | 158.0 | 186 | 97 | 91 | 24 | 58 | 153 | 0 | 0 | 0 | 0 | 14 | 5 | 5 | 4.23 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 78 | 27 | 27 | 8 | 13 | 6.33 | .359 | 1.65 | 11.7 | 3.2 | 7.4 | 166.1 | 216 | 127 | 117 | 30 | 59 | 136 | 1 | 0 | 0 | 0 | 12 | 5 | 5 | 4.87 |
| SP | Mussina, M.Mussina, Mike # >> | 33 | 2001 | R | 67 | 27 | 27 | 10 | 8 | 5.21 | .304 | 1.28 | 9.6 | 1.9 | 7.0 | 183.0 | 196 | 106 | 106 | 32 | 38 | 142 | 4 | 0 | 0 | 0 | 10 | 6 | 5 | 4.44 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 96 | 71 | 0 | 2 | 2 | 3.00 | .311 | 1.32 | 7.6 | 4.3 | 9.7 | 87.0 | 73 | 29 | 29 | 5 | 42 | 94 | 0 | 4 | 6 | 0 | 0 | 3 | 0 | 3.14 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 72 | 0 | 6 | 7 | 3.52 | .288 | 1.17 | 8.1 | 2.5 | 9.5 | 99.2 | 89 | 39 | 39 | 9 | 28 | 104 | 0 | 10 | 7 | 0 | 0 | 4 | 4 | 3.05 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 60 | 0 | 6 | 4 | 3.50 | .275 | 1.14 | 8.0 | 2.3 | 8.2 | 69.1 | 61 | 27 | 27 | 11 | 18 | 63 | 0 | 10 | 4 | 0 | 0 | 0 | 0 | 4.03 |
| RP | Politte, C.Politte, Cliff # >> | 31 | 2005 | R | 67 | 37 | 0 | 2 | 2 | 4.61 | .328 | 1.39 | 8.8 | 3.7 | 4.4 | 41.0 | 40 | 21 | 21 | 8 | 17 | 20 | 0 | 3 | 2 | 0 | 0 | 3 | 1 | 6.02 |
| RP | Mantei, M.Mantei, Matt # >> | 30 | 2003 | R | 61 | 37 | 0 | 1 | 3 | 6.75 | .345 | 1.58 | 9.5 | 5.0 | 10.7 | 38.2 | 40 | 29 | 29 | 10 | 21 | 45 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 5.71 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 48 | 14 | 0 | 2 | 2 | 5.91 | .326 | 1.45 | 9.4 | 3.9 | 7.7 | 21.1 | 22 | 14 | 14 | 5 | 9 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.67 |