| SP | Verlander, J.Verlander, Justin $$ >> | 36 | 2019 | R | 99 | 34 | 34 | 12 | 13 | 3.76 | .304 | 1.29 | 8.3 | 3.3 | 7.8 | 234.2 | 216 | 103 | 98 | 26 | 86 | 204 | 4 | 0 | 0 | 2 | 23 | 5 | 2 | 3.87 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 33 | 33 | 8 | 15 | 5.18 | .308 | 1.33 | 9.3 | 2.7 | 8.7 | 203.1 | 210 | 125 | 117 | 39 | 60 | 197 | 1 | 0 | 0 | 0 | 14 | 2 | 10 | 4.47 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 30 | 30 | 7 | 13 | 4.43 | .310 | 1.32 | 8.9 | 3.1 | 4.7 | 209.1 | 206 | 118 | 103 | 25 | 71 | 108 | 5 | 0 | 0 | 1 | 17 | 5 | 0 | 4.61 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 32 | 32 | 12 | 14 | 6.16 | .342 | 1.54 | 10.7 | 3.2 | 5.8 | 207.1 | 245 | 149 | 142 | 34 | 74 | 134 | 2 | 0 | 0 | 0 | 8 | 5 | 1 | 4.99 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 10 | 16 | 5.79 | .354 | 1.61 | 9.8 | 4.8 | 5.3 | 178.2 | 193 | 126 | 115 | 22 | 95 | 105 | 0 | 0 | 0 | 0 | 13 | 6 | 9 | 5.13 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 85 | 0 | 1 | 5 | 3.73 | .306 | 1.32 | 7.1 | 4.8 | 7.4 | 91.2 | 72 | 43 | 38 | 13 | 49 | 75 | 0 | 3 | 4 | 0 | 0 | 0 | 3 | 4.82 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 62 | 0 | 6 | 2 | 4.95 | .337 | 1.49 | 10.6 | 3.0 | 10.1 | 63.2 | 74 | 35 | 35 | 10 | 21 | 71 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 3.90 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 40 | 0 | 2 | 2 | 4.10 | .324 | 1.39 | 8.1 | 4.6 | 10.1 | 41.2 | 37 | 19 | 19 | 4 | 21 | 46 | 0 | 1 | 2 | 0 | 0 | 2 | 2 | 3.71 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 20 | 1 | 1 | 3 | 5.21 | .349 | 1.59 | 10.2 | 4.2 | 7.3 | 86.1 | 97 | 51 | 50 | 12 | 40 | 70 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 4.65 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 7 | 1 | 1 | 1 | 1.69 | .213 | 0.81 | 5.1 | 2.3 | 3.9 | 16.0 | 9 | 3 | 3 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 3.69 |