| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 6 | 6 | 0 | 4 | 8.13 | .368 | 1.75 | 10.3 | 5.6 | 9.5 | 34.1 | 39 | 32 | 31 | 4 | 21 | 36 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4.26 |
| SP | Alexander, P.Alexander, Pete $ >> | 28 | 1915 | R | 88 | 5 | 5 | 2 | 2 | 4.58 | .309 | 1.31 | 9.2 | 2.7 | 3.9 | 37.1 | 38 | 19 | 19 | 7 | 11 | 16 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 5.57 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 5 | 5 | 3 | 1 | 3.52 | .272 | 1.12 | 8.1 | 2.1 | 3.3 | 38.1 | 34 | 16 | 15 | 5 | 9 | 14 | 1 | 0 | 0 | 0 | 4 | 0 | 1 | 4.68 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 5 | 5 | 4 | 1 | 3.90 | .297 | 1.21 | 7.6 | 3.4 | 8.7 | 32.1 | 27 | 14 | 14 | 3 | 12 | 31 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 3.59 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 5 | 5 | 3 | 1 | 4.46 | .299 | 1.28 | 9.8 | 1.9 | 5.3 | 34.1 | 37 | 17 | 17 | 4 | 7 | 20 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 3.97 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 10 | 0 | 0 | 0 | 0.71 | .136 | 0.47 | 3.0 | 1.5 | 7.5 | 12.2 | 4 | 1 | 1 | 1 | 2 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 8 | 0 | 2 | 0 | 2.35 | .233 | 0.91 | 5.1 | 3.9 | 14.1 | 7.2 | 4 | 2 | 2 | 1 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 4 | 0 | 0 | 0 | 12.00 | .400 | 2.00 | 12.0 | 6.0 | 15.0 | 3.0 | 4 | 4 | 4 | 1 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 2 | 0 | 0 | 0 | 3.60 | .400 | 1.80 | 7.2 | 9.0 | 0.0 | 5.0 | 4 | 2 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.60 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 2 | 0 | 0 | 1 | 3.12 | .188 | 0.69 | 6.8 | 0.0 | 5.6 | 8.2 | 6 | 3 | 3 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 8 | 0 | 1 | 1 | 1.00 | .156 | 0.56 | 2.0 | 3.0 | 13.0 | 9.0 | 2 | 1 | 1 | 0 | 3 | 13 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 1.11 |