| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 12 | 15 | 4.49 | .303 | 1.29 | 9.4 | 2.2 | 7.3 | 222.1 | 233 | 119 | 111 | 36 | 54 | 179 | 1 | 0 | 0 | 0 | 17 | 3 | 7 | 4.27 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 33 | 33 | 13 | 9 | 3.68 | .296 | 1.24 | 7.7 | 3.5 | 5.5 | 213.0 | 183 | 94 | 87 | 17 | 82 | 130 | 1 | 0 | 0 | 0 | 23 | 4 | 3 | 4.03 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 32 | 31 | 10 | 15 | 4.61 | .306 | 1.28 | 8.5 | 3.0 | 5.2 | 195.1 | 185 | 111 | 100 | 23 | 66 | 113 | 5 | 0 | 0 | 2 | 15 | 7 | 3 | 4.50 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 90 | 0 | 6 | 3 | 4.32 | .301 | 1.26 | 7.3 | 4.2 | 5.4 | 93.2 | 75 | 47 | 45 | 10 | 43 | 56 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 4.68 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 70 | 0 | 5 | 2 | 3.78 | .320 | 1.41 | 8.7 | 4.2 | 8.3 | 78.2 | 75 | 33 | 33 | 12 | 36 | 72 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.54 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 87 | 0 | 9 | 10 | 5.11 | .321 | 1.41 | 9.1 | 3.6 | 8.1 | 88.0 | 89 | 54 | 50 | 10 | 35 | 79 | 0 | 32 | 9 | 0 | 0 | 1 | 1 | 3.91 |