| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 6 | 6 | 2 | 2 | 6.38 | .333 | 1.47 | 10.8 | 2.8 | 8.5 | 36.2 | 43 | 26 | 26 | 9 | 11 | 34 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 5.36 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 68 | 5 | 5 | 1 | 1 | 6.29 | .348 | 1.57 | 11.1 | 3.2 | 6.6 | 34.1 | 42 | 25 | 24 | 4 | 12 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4.21 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 5 | 5 | 2 | 2 | 4.75 | .316 | 1.39 | 7.0 | 5.5 | 6.5 | 36.0 | 28 | 19 | 19 | 3 | 22 | 26 | 1 | 0 | 0 | 0 | 2 | 0 | 2 | 4.47 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 62 | 5 | 5 | 0 | 3 | 8.34 | .387 | 1.90 | 9.0 | 8.6 | 4.5 | 22.2 | 22 | 22 | 21 | 4 | 21 | 11 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 7.23 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 4 | 4 | 1 | 0 | 7.85 | .368 | 1.75 | 10.0 | 6.0 | 9.0 | 18.1 | 20 | 16 | 16 | 2 | 12 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.44 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 14 | 0 | 1 | 0 | 2.91 | .226 | 0.83 | 5.6 | 2.1 | 7.3 | 21.2 | 13 | 7 | 7 | 3 | 5 | 17 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 15 | 0 | 1 | 1 | 4.80 | .348 | 1.53 | 9.0 | 4.8 | 7.2 | 15.0 | 15 | 8 | 8 | 3 | 8 | 12 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.80 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 13 | 0 | 1 | 1 | 3.12 | .288 | 1.21 | 7.9 | 3.2 | 13.2 | 17.1 | 15 | 6 | 6 | 2 | 6 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.65 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 48 | 2 | 0 | 1 | 0 | 1.50 | .217 | 0.83 | 7.5 | 0.0 | 6.0 | 6.0 | 5 | 1 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 6 | 1 | 0 | 2 | 6.35 | .346 | 1.59 | 10.6 | 4.1 | 8.2 | 11.1 | 13 | 8 | 8 | 5 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 8.45 |