| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 33 | 33 | 12 | 12 | 4.76 | .295 | 1.23 | 8.4 | 2.7 | 8.8 | 193.0 | 181 | 106 | 102 | 35 | 57 | 188 | 0 | 0 | 0 | 0 | 17 | 4 | 0 | 4.36 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 32 | 32 | 10 | 11 | 4.50 | .284 | 1.16 | 8.3 | 2.1 | 8.1 | 200.0 | 184 | 101 | 100 | 28 | 47 | 181 | 3 | 0 | 0 | 0 | 16 | 7 | 2 | 3.82 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 87 | 0 | 4 | 4 | 2.67 | .277 | 1.13 | 6.1 | 4.1 | 10.1 | 97.2 | 66 | 33 | 29 | 7 | 44 | 109 | 0 | 34 | 3 | 0 | 0 | 2 | 5 | 3.11 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 96 | 0 | 11 | 3 | 3.76 | .281 | 1.14 | 8.0 | 2.3 | 8.6 | 127.0 | 113 | 55 | 53 | 9 | 32 | 121 | 0 | 3 | 5 | 0 | 0 | 4 | 1 | 2.87 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 87 | 0 | 2 | 3 | 4.33 | .325 | 1.42 | 8.2 | 4.6 | 5.4 | 104.0 | 95 | 63 | 50 | 11 | 53 | 62 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.77 |