| SP | Burnes, C.Burnes, Corbin # >> | 27 | 2022 | R | 94 | 12 | 12 | 3 | 7 | 4.30 | .331 | 1.45 | 9.6 | 3.5 | 10.2 | 73.1 | 78 | 35 | 35 | 8 | 28 | 83 | 0 | 0 | 0 | 0 | 7 | 3 | 1 | 3.42 |
| SP | Mikolas, M.Mikolas, Miles >> | 33 | 2022 | R | 74 | 12 | 12 | 6 | 5 | 4.64 | .322 | 1.37 | 9.5 | 3.0 | 7.1 | 75.2 | 79 | 41 | 39 | 10 | 25 | 59 | 0 | 0 | 0 | 0 | 5 | 4 | 2 | 4.32 |
| SP | Wacha, M.Wacha, Michael >> | 30 | 2022 | R | 67 | 12 | 12 | 6 | 3 | 3.64 | .290 | 1.15 | 7.3 | 3.1 | 6.6 | 76.2 | 62 | 31 | 31 | 9 | 26 | 56 | 0 | 0 | 0 | 0 | 8 | 6 | 2 | 4.33 |
| RP | Munoz, A.Munoz, Andres >> | 23 | 2022 | R | 97 | 32 | 0 | 1 | 1 | 4.06 | .304 | 1.22 | 8.2 | 2.9 | 10.2 | 44.1 | 40 | 20 | 20 | 5 | 14 | 50 | 0 | 1 | 2 | 0 | 0 | 4 | 1 | 3.43 |
| RP | Garrett, A.Garrett, Amir >> | 30 | 2022 | L | 55 | 28 | 0 | 1 | 2 | 4.50 | .408 | 2.00 | 8.7 | 9.3 | 10.6 | 28.0 | 27 | 14 | 14 | 4 | 29 | 33 | 0 | 6 | 1 | 0 | 0 | 2 | 2 | 5.82 |
| RP | Strahm, M.Strahm, Matt >> | 30 | 2022 | L | 46 | 23 | 0 | 1 | 2 | 4.50 | .321 | 1.33 | 7.9 | 4.1 | 8.6 | 24.0 | 21 | 12 | 12 | 4 | 11 | 23 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 4.88 |
| SP | Manaea, S.Manaea, Sean >> | 30 | 2022 | L | 38 | 3 | 0 | 1 | 0 | 11.57 | .462 | 2.36 | 22.5 | 2.3 | 9.0 | 4.2 | 10 | 6 | 6 | 3 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 12.25 |