| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 100 | 4 | 4 | 0 | 1 | 6.16 | .352 | 1.58 | 11.4 | 2.8 | 9.9 | 19.0 | 24 | 14 | 13 | 1 | 6 | 21 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 2.58 |
| SP | Ohtani, S.Ohtani, Shohei >> | 27 | 2022 | R | 89 | 4 | 4 | 1 | 1 | 5.40 | .333 | 1.50 | 11.0 | 2.7 | 9.8 | 23.1 | 28 | 14 | 14 | 4 | 7 | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.00 |
| SP | Anderson, T.Anderson, Tyler >> | 32 | 2022 | L | 80 | 4 | 4 | 0 | 3 | 7.23 | .371 | 1.71 | 12.0 | 4.0 | 9.5 | 18.2 | 24 | 15 | 15 | 4 | 8 | 19 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 5.28 |
| SP | Rasmussen, D.Rasmussen, Drew >> | 26 | 2022 | R | 75 | 3 | 3 | 1 | 0 | 3.60 | .318 | 1.27 | 9.0 | 2.4 | 6.6 | 15.0 | 15 | 6 | 6 | 0 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2.73 |
| RP | Murfee, P.Murfee, Penn >> | 28 | 2022 | R | 87 | 6 | 0 | 0 | 2 | 12.00 | .419 | 2.17 | 10.5 | 9.0 | 6.0 | 6.0 | 7 | 8 | 8 | 1 | 6 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.83 |
| RP | Iglesias, R.Iglesias, Raisel >> | 32 | 2022 | R | 84 | 6 | 0 | 1 | 0 | 5.40 | .259 | 1.05 | 10.5 | 0.0 | 15.0 | 6.2 | 7 | 4 | 4 | 3 | 0 | 10 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 6.17 |
| RP | McHugh, C.McHugh, Collin >> | 35 | 2022 | R | 83 | 5 | 0 | 1 | 1 | 5.14 | .344 | 1.57 | 14.1 | 0.0 | 9.0 | 7.0 | 11 | 4 | 4 | 0 | 0 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | Hendriks, L.Hendriks, Liam >> | 33 | 2022 | R | 74 | 6 | 0 | 1 | 0 | 5.40 | .348 | 1.60 | 10.8 | 3.6 | 5.4 | 5.0 | 6 | 3 | 3 | 1 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.60 |
| SP | Wright, K.Wright, Kyle >> | 26 | 2022 | R | 65 | 2 | 0 | 1 | 0 | 10.80 | .444 | 2.40 | 16.2 | 5.4 | 7.2 | 5.0 | 9 | 6 | 6 | 1 | 3 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.80 |