| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 97 | 12 | 12 | 7 | 4 | 3.69 | .280 | 1.09 | 7.5 | 2.3 | 9.0 | 78.0 | 65 | 33 | 32 | 6 | 20 | 78 | 1 | 0 | 0 | 0 | 8 | 6 | 1 | 3.00 |
| SP | Kelly, M.Kelly, Merrill >> | 33 | 2022 | R | 71 | 12 | 12 | 5 | 3 | 4.33 | .314 | 1.33 | 8.6 | 3.5 | 7.2 | 70.2 | 67 | 34 | 34 | 8 | 27 | 56 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 4.17 |
| CL | Phillips, E.Phillips, Evan >> | 27 | 2022 | R | 98 | 23 | 0 | 4 | 1 | 1.75 | .198 | 0.70 | 3.2 | 3.2 | 10.4 | 25.2 | 9 | 5 | 5 | 2 | 9 | 29 | 0 | 15 | 1 | 0 | 0 | 1 | 0 | 2.92 |
| RP | Iglesias, R.Iglesias, Raisel >> | 32 | 2022 | R | 84 | 24 | 0 | 0 | 1 | 4.01 | .288 | 1.22 | 7.5 | 3.8 | 12.4 | 24.2 | 20 | 11 | 11 | 5 | 10 | 33 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Romano, J.Romano, Jordan >> | 29 | 2022 | R | 80 | 15 | 0 | 4 | 0 | 3.66 | .263 | 1.07 | 6.2 | 3.8 | 9.9 | 19.2 | 13 | 8 | 8 | 1 | 8 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.74 |
| RP | Lopez, R.Lopez, Reynaldo >> | 28 | 2022 | R | 75 | 9 | 0 | 2 | 1 | 4.70 | .361 | 1.70 | 14.1 | 2.6 | 7.7 | 7.2 | 11 | 4 | 4 | 0 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.14 |
| RP | Tepera, R.Tepera, Ryan >> | 34 | 2022 | R | 68 | 6 | 0 | 0 | 0 | 0.00 | .143 | 0.50 | 1.5 | 3.0 | 4.5 | 6.0 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Bickford, P.Bickford, Phil >> | 26 | 2022 | R | 61 | 9 | 0 | 0 | 0 | 2.61 | .295 | 1.26 | 10.8 | 0.9 | 10.8 | 10.1 | 12 | 3 | 3 | 0 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.90 |