| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 97 | 18 | 18 | 7 | 10 | 4.09 | .310 | 1.34 | 10.5 | 1.6 | 11.3 | 114.1 | 133 | 54 | 52 | 9 | 20 | 143 | 0 | 0 | 0 | 0 | 11 | 1 | 2 | 2.07 |
| SP | Wheeler, Z.Wheeler, Zack >> | 32 | 2022 | R | 82 | 17 | 17 | 5 | 10 | 4.86 | .344 | 1.57 | 12.0 | 2.2 | 10.0 | 87.0 | 116 | 51 | 47 | 9 | 21 | 97 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 2.84 |
| SP | Garcia, L.Garcia, Luis >> | 25 | 2022 | R | 75 | 17 | 17 | 6 | 3 | 7.20 | .355 | 1.57 | 11.3 | 2.9 | 9.8 | 75.0 | 94 | 60 | 60 | 17 | 24 | 82 | 0 | 0 | 0 | 0 | 5 | 6 | 8 | 4.96 |
| SP | Wright, K.Wright, Kyle # >> | 26 | 2022 | R | 65 | 18 | 17 | 6 | 8 | 5.52 | .320 | 1.38 | 9.7 | 2.7 | 9.7 | 93.0 | 100 | 57 | 57 | 13 | 28 | 100 | 0 | 1 | 0 | 0 | 8 | 3 | 2 | 3.67 |
| RP | Swanson, E.Swanson, Erik >> | 28 | 2022 | R | 90 | 51 | 0 | 2 | 2 | 2.80 | .328 | 1.39 | 10.3 | 2.3 | 13.0 | 54.2 | 62 | 20 | 17 | 4 | 14 | 78 | 0 | 1 | 2 | 0 | 0 | 4 | 3 | 2.07 |
| RP | McHugh, C.McHugh, Collin >> | 35 | 2022 | R | 83 | 34 | 0 | 2 | 1 | 3.96 | .351 | 1.60 | 10.5 | 4.0 | 11.0 | 36.1 | 42 | 16 | 16 | 3 | 16 | 44 | 0 | 0 | 2 | 0 | 0 | 1 | 3 | 3.06 |
| RP | Lopez, R.Lopez, Reynaldo >> | 28 | 2022 | R | 75 | 22 | 0 | 0 | 1 | 3.29 | .299 | 1.28 | 10.7 | 1.0 | 10.7 | 27.1 | 32 | 11 | 10 | 4 | 3 | 32 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.89 |
| RP | Iglesias, R.Iglesias, Raisel >> | 32 | 2022 | R | 84 | 25 | 0 | 1 | 2 | 5.09 | .343 | 1.30 | 9.4 | 2.3 | 10.6 | 23.0 | 24 | 13 | 13 | 2 | 6 | 27 | 0 | 0 | 1 | 0 | 0 | 6 | 2 | 3.35 |