| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 7 | 7 | 4 | 1 | 3.64 | .258 | 1.04 | 7.5 | 2.0 | 9.2 | 59.1 | 49 | 24 | 24 | 5 | 13 | 60 | 1 | 0 | 0 | 1 | 4 | 0 | 0 | 2.73 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 7 | 7 | 5 | 2 | 3.06 | .260 | 1.04 | 6.5 | 2.9 | 9.7 | 53.0 | 38 | 21 | 18 | 4 | 17 | 57 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 2.85 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 7 | 7 | 1 | 3 | 2.84 | .296 | 1.26 | 7.8 | 3.7 | 8.6 | 44.1 | 38 | 14 | 14 | 6 | 18 | 42 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 4.09 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 77 | 7 | 7 | 3 | 3 | 4.30 | .305 | 1.32 | 8.5 | 3.5 | 7.6 | 52.1 | 49 | 25 | 25 | 5 | 20 | 44 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.71 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 18 | 0 | 2 | 1 | 3.32 | .226 | 0.83 | 6.4 | 1.3 | 9.4 | 21.2 | 15 | 9 | 8 | 3 | 3 | 22 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.33 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 9 | 0 | 0 | 0 | 3.65 | .260 | 0.97 | 7.5 | 1.5 | 8.3 | 12.1 | 10 | 5 | 5 | 2 | 2 | 11 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.08 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 90 | 5 | 0 | 0 | 2 | 9.53 | .320 | 1.24 | 10.8 | 1.8 | 9.0 | 5.2 | 6 | 6 | 6 | 3 | 1 | 5 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 10.00 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 5 | 0 | 0 | 1 | 2.45 | .353 | 1.64 | 12.0 | 6.0 | 6.0 | 3.2 | 4 | 1 | 1 | 0 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 3 | 0 | 0 | 0 | 0.00 | .200 | 0.75 | 9.0 | 0.0 | 18.0 | 2.2 | 2 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 2 | 0 | 0 | 0 | 7.88 | .442 | 2.38 | 15.8 | 5.6 | 7.9 | 8.0 | 14 | 7 | 7 | 1 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |