| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 12 | 12 | 4 | 3 | 5.24 | .320 | 1.40 | 9.1 | 3.6 | 5.8 | 68.2 | 69 | 41 | 40 | 14 | 27 | 44 | 1 | 0 | 0 | 0 | 5 | 1 | 2 | 5.62 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 54 | 12 | 12 | 4 | 7 | 5.31 | .322 | 1.39 | 10.2 | 2.4 | 8.2 | 76.1 | 86 | 47 | 45 | 15 | 20 | 69 | 1 | 0 | 0 | 0 | 4 | 3 | 2 | 4.66 |
| SP | Dempster, R.Dempster, Ryan >> | 31 | 2008 | R | 38 | 11 | 11 | 0 | 6 | 8.87 | .419 | 2.16 | 13.1 | 6.7 | 8.8 | 46.2 | 67 | 47 | 46 | 18 | 34 | 45 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 8.35 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 59 | 33 | 0 | 1 | 4 | 5.84 | .319 | 1.38 | 8.5 | 3.9 | 11.2 | 37.0 | 35 | 24 | 24 | 8 | 16 | 46 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 4.70 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 38 | 29 | 0 | 1 | 1 | 7.12 | .364 | 1.71 | 10.8 | 4.8 | 6.6 | 30.1 | 36 | 25 | 24 | 7 | 16 | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 6.17 |
| RP | Corpas, M.Corpas, Manuel >> | 25 | 2007 | R | 22 | 19 | 0 | 0 | 0 | 5.40 | .337 | 1.52 | 10.3 | 3.9 | 7.3 | 21.2 | 24 | 15 | 13 | 6 | 9 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.38 |
| RP | Carrara, G.Carrara, Giovanni >> | 33 | 2001 | R | 11 | 23 | 0 | 3 | 2 | 4.10 | .336 | 1.52 | 10.4 | 3.5 | 6.9 | 26.1 | 30 | 17 | 12 | 6 | 10 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.62 |
| SP | Volquez, E.Volquez, Edinson >> | 25 | 2008 | R | 24 | 16 | 0 | 2 | 0 | 6.84 | .364 | 1.72 | 11.2 | 4.3 | 11.2 | 25.0 | 31 | 19 | 19 | 4 | 12 | 31 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.04 |