| SP | Schilling, C.Schilling, Curt # >> | 36 | 2002 | R | 93 | 24 | 24 | 5 | 13 | 4.29 | .301 | 1.27 | 9.6 | 1.9 | 9.9 | 178.1 | 189 | 88 | 85 | 17 | 37 | 195 | 6 | 0 | 0 | 1 | 13 | 4 | 2 | 2.74 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 26 | 2006 | R | 93 | 58 | 0 | 4 | 6 | 4.62 | .319 | 1.39 | 8.1 | 4.5 | 8.4 | 76.0 | 68 | 43 | 39 | 8 | 38 | 71 | 0 | 5 | 1 | 0 | 0 | 1 | 4 | 4.04 |
| RP | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 64 | 57 | 0 | 2 | 1 | 4.71 | .313 | 1.35 | 8.8 | 3.5 | 10.5 | 78.1 | 76 | 42 | 41 | 12 | 30 | 91 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 3.86 |
| RP | Howell, J.Howell, J.P. >> | 25 | 2008 | L | 32 | 36 | 0 | 0 | 1 | 2.62 | .283 | 1.16 | 6.1 | 4.5 | 10.0 | 44.2 | 30 | 14 | 13 | 3 | 22 | 49 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.23 |
| RP | Seanez, R.Seanez, Rudy >> | 37 | 2005 | R | 20 | 32 | 0 | 1 | 1 | 2.35 | .281 | 1.17 | 6.4 | 4.3 | 10.9 | 38.1 | 27 | 10 | 10 | 5 | 18 | 46 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 3.71 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 47 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Colon, B.Colon, Bartolo >> | 32 | 2005 | R | 22 | 1 | 0 | 0 | 1 | 13.50 | .667 | 6.00 | - | - | - | 0.2 | 2 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Patterson, J.Patterson, John >> | 27 | 2005 | R | 33 | 9 | 0 | 0 | 0 | 5.56 | .382 | 1.85 | 13.1 | 4.1 | 9.0 | 11.1 | 16 | 8 | 7 | 3 | 5 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.91 |